CAS 60477-34-1

CYCLIC-PIFITHRIN-ALPHA

Description:

Cyclic-Pifithrin-Alpha, identified by its CAS number 60477-34-1, is a chemical compound that belongs to a class of molecules known for their potential biological activity, particularly in the context of cellular stress responses. This compound is characterized by its cyclic structure, which contributes to its stability and reactivity. Cyclic-Pifithrin-Alpha is primarily studied for its role as a selective inhibitor of the heat shock response, which is crucial in various physiological and pathological processes, including cancer and neurodegenerative diseases. The compound's mechanism of action involves modulation of heat shock proteins, which are essential for protein folding and protection against cellular stress. In terms of physical properties, it is typically a solid at room temperature, with solubility varying based on the solvent used. Safety data and handling precautions should be observed, as with any chemical substance, to mitigate potential hazards during research and application. Further studies are ongoing to fully elucidate its therapeutic potential and mechanisms of action in biological systems.

Formula: C₁₆H₁₆N₂S

Synonyms:

• Pifithrin-β (QB-102 and Cyclic-Pifithrin-α)
• Imidazo[2,1-b]benzothiazole, 5,6,7,8-tetrahydro-2-(4-methylphenyl)-
• Pifithrin-α, Cyclic- - CAS 60477-34-1 - Calbiochem
• Pifithrin-2
• 5,6,7,8-Tetrahydro-2-(4-methylphenyl)-imidazo[2,1-b]benzothiazole
• Pifithrin-alpha (cyclic) . HBr

Pifithrin-β

CAS: 60477-34-1

potent p53 inhibitor

Formula: C₁₆H₁₆N₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 268.38

Ref: TM-T23156

Pifithrin-²

CAS: 60477-34-1

Pifithrin-² is a linker enzyme that catalyzes the transfer of electrons from NADPH to an electron acceptor, such as oxygen. Pifithrin-2 has been shown to be active against imidazole resistant organisms, including methicillin resistant Staphylococcus aureus (MRSA). Pifithrin-2 also has been shown to have high activity against eukaryotic organisms and can be used for the treatment of diseases caused by these organisms. The reaction rate of pifithrin-2 depends on its proximity to the substrate binding site and kinetic analysis shows that it binds with high affinity.

Formula: C₁₆H₁₆N₂S

Purity: Min. 95%

Molecular weight: 268.38 g/mol

Ref: 3D-KCA47734