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CAS 60482-95-3

:

neurotensin fragment 8-13 acetate

Description:
Neurotensin fragment 8-13 acetate, identified by its CAS number 60482-95-3, is a peptide derived from the neurotensin molecule, which plays a significant role in various physiological processes, including pain modulation, regulation of body temperature, and the stimulation of dopamine release. This specific fragment consists of a sequence of amino acids that are crucial for its biological activity. The acetate form indicates that the peptide is acetylated, which can enhance its stability and bioavailability. Neurotensin and its fragments are known to interact with neurotensin receptors, influencing neurotransmission and potentially impacting conditions such as schizophrenia and obesity. The characteristics of this peptide include its solubility in aqueous solutions, stability under physiological conditions, and its potential use in research and therapeutic applications. As a synthetic peptide, it is typically produced through solid-phase peptide synthesis, ensuring high purity and specific activity for experimental use.
Formula:C38H64N12O8
InChI:InChI=1/C38H64N12O8/c1-5-22(4)30(34(55)48-28(36(57)58)19-21(2)3)49-32(53)27(20-23-12-14-24(51)15-13-23)47-33(54)29-11-8-18-50(29)35(56)26(10-7-17-45-38(42)43)46-31(52)25(39)9-6-16-44-37(40)41/h12-15,21-22,25-30,51H,5-11,16-20,39H2,1-4H3,(H,46,52)(H,47,54)(H,48,55)(H,49,53)(H,57,58)(H4,40,41,44)(H4,42,43,45)/t22-,25-,26-,27-,28?,29-,30-/m0/s1
SMILES:CC[C@H](C)[C@@H](C(=NC(CC(C)C)C(=O)O)O)N=C([C@H](Cc1ccc(cc1)O)N=C([C@@H]1CCCN1C(=O)[C@H](CCCNC(=N)N)N=C([C@H](CCCNC(=N)N)N)O)O)O
Synonyms:
  • Neurotensin (8-13)
  • H-Arg-Arg-Pro-Tyr-Ile-Leu-OH
  • N~5~-(diaminomethylidene)-L-ornithyl-N~5~-(diaminomethylidene)-L-ornithyl-L-prolyl-L-tyrosyl-L-isoleucylleucine
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