CAS 60482-95-3

neurotensin fragment 8-13 acetate

Description:

Neurotensin fragment 8-13 acetate, identified by its CAS number 60482-95-3, is a peptide derived from the neurotensin molecule, which plays a significant role in various physiological processes, including pain modulation, regulation of body temperature, and the stimulation of dopamine release. This specific fragment consists of a sequence of amino acids that are crucial for its biological activity. The acetate form indicates that the peptide is acetylated, which can enhance its stability and bioavailability. Neurotensin and its fragments are known to interact with neurotensin receptors, influencing neurotransmission and potentially impacting conditions such as schizophrenia and obesity. The characteristics of this peptide include its solubility in aqueous solutions, stability under physiological conditions, and its potential use in research and therapeutic applications. As a synthetic peptide, it is typically produced through solid-phase peptide synthesis, ensuring high purity and specific activity for experimental use.

Formula: C₃₈H₆₄N₁₂O₈

InChI: InChI=1/C38H64N12O8/c1-5-22(4)30(34(55)48-28(36(57)58)19-21(2)3)49-32(53)27(20-23-12-14-24(51)15-13-23)47-33(54)29-11-8-18-50(29)35(56)26(10-7-17-45-38(42)43)46-31(52)25(39)9-6-16-44-37(40)41/h12-15,21-22,25-30,51H,5-11,16-20,39H2,1-4H3,(H,46,52)(H,47,54)(H,48,55)(H,49,53)(H,57,58)(H4,40,41,44)(H4,42,43,45)/t22-,25-,26-,27-,28?,29-,30-/m0/s1

SMILES: CC[C@H](C)[C@@H](C(=NC(CC(C)C)C(=O)O)O)N=C([C@H](Cc1ccc(cc1)O)N=C([C@@H]1CCCN1C(=O)[C@H](CCCNC(=N)N)N=C([C@H](CCCNC(=N)N)N)O)O)O

Synonyms:

• Neurotensin (8-13)
• H-Arg-Arg-Pro-Tyr-Ile-Leu-OH
• N~5~-(diaminomethylidene)-L-ornithyl-N~5~-(diaminomethylidene)-L-ornithyl-L-prolyl-L-tyrosyl-L-isoleucylleucine

Neurotensin (8-13)

CAS: 60482-95-3

Bachem ID: 4008910.

Formula: C₃₈H₆₄N₁₂O₈

Purity: 99.3%

Color and Shape: White Powder

Molecular weight: 817.0

Ref: 01-4008910

Neurotensin (8-13)

CAS: 60482-95-3

The sequence RRPYIL is essential for neurotensin-NT receptor interaction.

Formula: C₃₈H₆₄N₁₂O₈

Purity: 99.4%

Color and Shape: White Powder

Molecular weight: 817.0

Ref: 01-4100575

Neurotensin (8-13) H-Arg-Arg-Pro-Tyr-Ile-Leu-OH

CAS: 60482-95-3

Formula: C₃₈H₆₄N₁₂O₈

Purity: 97%

Color and Shape: Solid

Molecular weight: 816.9904

Ref: IN-DA01EA56

Neurotensin(8-13)

CAS: 60482-95-3

Neurotensin(8-13)

Purity: ≥98%

Molecular weight: 816.99g/mol

Ref: 54-BUP21981

Neurotensin(8-13)

CAS: 60482-95-3

Neurotensin(8-13) is Neurotensin (NT) fragment, Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density.

Formula: C₃₈H₆₄N₁₂O₈

Purity: 99.95%

Color and Shape: Solid

Molecular weight: 816.99

Ref: TM-T7617

L-ARGINYL-L-ARGINYL-L-PROLYL-L-TYROSYL-L-ISOLEUCYL-L-LEUCINE

CAS: 60482-95-3

Purity: ≥97%(HPLC)

Molecular weight: 817.0059814

Ref: 10-F840787

Neurotensin (8-13)

CAS: 60482-95-3

Neurotensin is a peptide that regulates the activity of the hypothalamus and pituitary gland. Neurotensin is synthesized from prepro-neurotensin, which is cleaved to produce neurotensin (8-13) H-Arg-Arg-Pro-Tyr-Ile-Leu-OH. It is a member of the tachykinins family of neuropeptides, which are characterized by a conserved disulfide bond. Neurotensin has been shown to increase locomotor activity in mice and rats and may be involved in pain perception. Neurotensin also binds to receptors on nerve cells, including the enkephalin receptor, with high affinity. This binding leads to an inhibition of release of neurotransmitters such as dopamine, serotonin, and acetylcholine by neurons.

Formula: C₃₈H₆₄N₁₂O₈

Purity: Min. 95%

Molecular weight: 816.99 g/mol

Ref: 3D-FN108541