CAS 60508-81-8

3-(2-deoxy-5-O-phosphono-beta-D-erythro-pentofuranosyl)-3H-imidazo[2,1-i]purine

Description:

3-(2-Deoxy-5-O-phosphono-beta-D-erythro-pentofuranosyl)-3H-imidazo[2,1-i]purine, commonly referred to as a nucleoside analog, exhibits several notable characteristics. This compound features a purine base linked to a deoxyribose sugar, which is further modified by a phosphonate group. The presence of the phosphono group enhances its solubility in aqueous solutions and can influence its biological activity, making it a subject of interest in medicinal chemistry, particularly in antiviral and anticancer research. The imidazo[2,1-i]purine structure contributes to its potential as a substrate for various enzymes, impacting its role in nucleic acid metabolism. Additionally, the compound's stereochemistry, specifically the beta-D-erythro configuration, is crucial for its interaction with biological targets. Overall, this substance is characterized by its unique structural features that facilitate its function as a nucleoside analog, with implications for therapeutic applications in the modulation of nucleic acid processes.

Formula: C₁₂H₁₄N₅O₆P

InChI: InChI=1/C12H14N5O6P/c18-7-3-9(23-8(7)4-22-24(19,20)21)17-6-14-10-11-13-1-2-16(11)5-15-12(10)17/h1-2,5-9,18H,3-4H2,(H2,19,20,21)/t7-,8+,9+/m0/s1

Synonyms:

• 2’-deoxy-1,N6-ethenoadenosine-5’-O-monophosphate
• Etheno-2’-deoxy-β-D-adenosine 5’-Monophosphate
• ε-5'-dAMP
• 3-(2-Deoxy-5-O-phosphono-β-D-erythro-pentofuranosyl)-3H-iMidazo[2,1-i]purine
• 3H-Imidazo[2,1-i]purine, 3-(2-deoxy-5-O-phosphono-β-D-erythro-pentofuranosyl)-
• Etheno-2'-deoxy-β-D-adenosine 5'-Monophosphate
• 1,N6-Etheno-2'-deoxy-AMP

Etheno-2’-deoxy-β-D-adenosine 5’-Monophosphate Sodium Salt

Controlled Product

CAS: 60508-81-8

Applications A phosphorylated adenosine derivative used as probes of the activator site of glycogen phosphorylase. It is used in method for detecting misincorporation during DNA synthesis.
References Vandenbunder, B. et al.: Proc, Nat. Acd. Sci. U.S.A., 73, 2696 (1976); Revich, G.G. et al.: Carcinogen., 7, 1569 (1986);

Formula: C₁₂H₁₃N₅NaO₆P

Color and Shape: Neat

Molecular weight: 377.23

Ref: TR-E890388

Etheno-2’-deoxy-β-D-adenosine 5’-Monophosphate

Controlled Product

CAS: 60508-81-8

Formula: C₁₂H₁₄N₅O₆P

Color and Shape: Neat

Molecular weight: 355.243

Ref: TR-E890385

Etheno-2'-deoxy-β-D-adenosine 5'-Monophosphate

CAS: 60508-81-8

Formula: C₁₂H₁₄N₅O₆P

Molecular weight: 355.24

Ref: ST-EA-CP-E293005