CAS 6051-87-2

β-Naphthoflavone

Description:

β-Naphthoflavone, with the CAS number 6051-87-2, is an organic compound that belongs to the class of flavonoids. It is characterized by its polycyclic structure, which consists of a naphthalene moiety fused to a flavone backbone. This compound is typically a yellow to orange crystalline solid and is known for its role as a ligand for the aryl hydrocarbon receptor (AhR), influencing various biological processes, including the metabolism of xenobiotics. β-Naphthoflavone exhibits antioxidant properties and has been studied for its potential effects on enzyme induction, particularly cytochrome P450 enzymes. It is soluble in organic solvents such as ethanol and dimethyl sulfoxide (DMSO) but has limited solubility in water. Due to its biological activity, β-Naphthoflavone is often used in research related to toxicology, pharmacology, and environmental science, particularly in studies examining the effects of environmental pollutants on biological systems. Safety data should be consulted for handling and exposure guidelines, as with any chemical substance.

Formula: C₁₉H₁₂O₂

InChI: InChI=1S/C19H12O2/c20-16-12-18(14-7-2-1-3-8-14)21-17-11-10-13-6-4-5-9-15(13)19(16)17/h1-12H

InChI key: InChIKey=OUGIDAPQYNCXRA-UHFFFAOYSA-N

SMILES: O=C1C2=C3C(=CC=C2OC(=C1)C4=CC=CC=C4)C=CC=C3

Synonyms:

• 3-Phenyl-1H-benzo[f]chromen-1-one
• 3-Phenyl-1H-naphtho[2,1-b]pyran-1-on
• 3-Phenylbenzo[f]chromen-1-one
• 3-fenil-1H-nafto[2,1-b]pirano-1-ona
• 3-phenyl-1H-naphtho[2,1-b]pyran-1-one
• 3-phenyl-1H-naphto[2,1-b]pyranne-1-one
• 5,6-Benzoflavone
• Nsc 136015
• β-Naphthoflavone
• 1H-Naphtho[2,1-b]pyran-1-one, 3-phenyl-

β-Naphthoflavone, 98+%

CAS: 6051-87-2

Inhibitor of aryl hydrocarbon hydroxylase This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a

Formula: C₁₉H₁₂O₂

Purity: 98+%

Color and Shape: White to cream, Crystals or powder or crystalline powder

Molecular weight: 272.30

Ref: 02-A18543

DULCITOL

CAS: 6051-87-2

Formula: C₁₉H₁₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 272.2974

Ref: IN-DA00E9F8

5,6-Benzoflavone

CAS: 6051-87-2

5,6-Benzoflavone

Purity: ≥98%

Molecular weight: 272.3g/mol

Ref: 54-BUP16670

5,6-Benzoflavone

CAS: 6051-87-2

5,6-Benzoflavone (β-Naphthoflavone) is an exogenous ligand for the aryl hydrocarbon receptor, has anti-inflammatory activity

Formula: C₁₉H₁₂O₂

Purity: 99.88%

Color and Shape: Slightly Beige Crystalline Powder

Molecular weight: 272.3

Ref: TM-TN6694

β-Naphthoflavone

CAS: 6051-87-2

Formula: C₁₉H₁₂O₂

Purity: ≤ 98.0%

Color and Shape: White to light yellow powder or crystals

Molecular weight: 272.31

Ref: 7W-GK6129

β-Naphthoflavone

CAS: 6051-87-2

β-Naphthoflavone

Purity: 99%

Color and Shape: Off-White Powder

Molecular weight: 272.29738g/mol

Ref: 54-OR1159

β-Naphthoflavone

CAS: 6051-87-2

Formula: C₁₉H₁₂O₂

Purity: >99.0%(GC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 272.30

Ref: 3B-N0518

beta-Naphthoflavone

CAS: 6051-87-2

Beta-Naphthoflavone is a synthetic polycyclic aromatic compound, which is a laboratory-created substance designed to mimic naturally occurring compounds. It is a model compound widely used in scientific research due to its ability to induce specific enzyme pathways. Beta-Naphthoflavone primarily affects the aryl hydrocarbon receptor (AhR) pathway. Upon binding to this receptor, it modulates the expression of genes involved in xenobiotic metabolism, particularly influencing the cytochrome P450 enzymes. These enzymes play a crucial role in the metabolism of various xenobiotics and endogenous compounds.

Formula: C₁₉H₁₂O₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 272.3 g/mol

Ref: 3D-FN35416

β-Naphthoflavone

CAS: 6051-87-2

Formula: C₁₉H₁₂O₂

Purity: 98%

Color and Shape: Liquid, No data available.

Molecular weight: 272.303

Ref: 10-F493719

Beta-Naphthoflavone

Controlled Product

CAS: 6051-87-2

Applications beta-Naphthoflavone is a Cytochrome P450 enzyme system inducer. It can also be used in biological study of novel dual-color luciferase reporter assay for simultaneous detection of estrogen and aryl hydrocarbon receptor activation.
References Tarnow, P., et al.: Chem Res Toxicol, 30, 1436 (2017)

Formula: C₁₉H₁₂O₂

Color and Shape: Neat

Molecular weight: 272.3

Ref: TR-N369015