CAS 60520-47-0

eosin 5-isothiocyanate

Description:

Eosin 5-isothiocyanate is a synthetic organic compound characterized by its vibrant red color, which is derived from the eosin dye family. It is primarily used as a fluorescent marker in biological and biochemical applications, particularly in the study of cellular processes and in histological staining. The compound features an isothiocyanate functional group, which enhances its reactivity, allowing it to form covalent bonds with nucleophilic sites in proteins and other biomolecules. This property makes it valuable for labeling and tracking proteins in various experimental settings. Eosin 5-isothiocyanate is soluble in organic solvents and exhibits fluorescence under specific wavelengths of light, making it useful for imaging techniques. Additionally, it is important to handle this compound with care, as isothiocyanates can be irritants and may pose health risks if proper safety protocols are not followed. Overall, eosin 5-isothiocyanate serves as a versatile tool in research, particularly in the fields of cell biology and biochemistry.

Formula: C₂₁H₇Br₄NO₅S

InChI: InChI=1S/C21H7Br4NO5S/c22-12-4-10-18(14(24)16(12)27)30-19-11(5-13(23)17(28)15(19)25)21(10)9-2-1-7(26-6-32)3-8(9)20(29)31-21/h1-5,27-28H

InChI key: InChIKey=XHXYXYGSUXANME-UHFFFAOYSA-N

SMILES: O=C1OC2(C=3C(OC=4C2=CC(Br)=C(O)C4Br)=C(Br)C(O)=C(Br)C3)C=5C1=CC(N=C=S)=CC5

Synonyms:

• 2',4',5',7'-tetrabromo-3',6'-dihydroxy-5-isothiocyanato-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one
• 2′,4′,5′,7′-Tetrabromo-3′,6′-dihydroxy-5-isothiocyanatospiro[isobenzofuran-1(3H),9′-[9H]xanthen]-3-one
• 5-Isothiocyanato-2-(2,4,5,7-tetrabromo-3-hydroxy-6-oxoxanthen-9-yl)benzoic acid
• 5-isothiocyanato-2-(2,4,5,7-tetrabromo-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid
• Eosin isothiocyanate
• Spiro[isobenzofuran-1(3H),9′-[9H]xanthen]-3-one, 2′,4′,5′,7′-tetrabromo-3′,6′-dihydroxy-5-isothiocyanato-
• Eosin-5-isothiocyanate
• Eosin 5-isothiocyanate

Eosin 5-isothiocyanate

CAS: 60520-47-0

Formula: C₂₁H₇Br₄NO₅S

Purity: 95%

Color and Shape: Solid

Molecular weight: 704.9650

Ref: IN-DA00E983

Eosin-5-isothiocyanate

CAS: 60520-47-0

Ref: 7W-GW1599

Eosine-5-isothiocyanate

Controlled Product

CAS: 60520-47-0

Applications Eosine-5-isothiocyanate is a fluorescence probe.

Formula: C₂₁H₇Br₄NO₅S

Color and Shape: Neat

Molecular weight: 704.96

Ref: TR-E561010

Eosine-5-isothiocyanate

CAS: 60520-47-0

Eosine-5-isothiocyanate is a fluorescent probe that has affinity for the interstitium of the kidney. This compound inhibits the transport of organic compounds across the renal tubular epithelium, and it is used as a marker for renal function. Eosine-5-isothiocyanate binds to molybdate with high affinity and can be used to measure its concentration in blood plasma. The inhibitory potency of eosine-5-isothiocyanate on carboxylates was tested by perfusing phenolphthalein through a rat's kidneys. Phenoxy dicarboxylates were found to be more potent inhibitors than phenoxy monocarboxylates, but not as potent as eosine-5-isothiocyanate itself. The spectrum of eosine-5-isothiocyanate is in the visible range, so this compound can be detected using

Formula: C₂₁H₇Br₄NO₅S

Purity: 85% Min

Color and Shape: Powder

Molecular weight: 704.97 g/mol

Ref: 3D-FE04409