CAS 6054-98-4

Olsalazine sodium

Description:

Olsalazine sodium is a chemical compound primarily used as a medication for the treatment of ulcerative colitis, a form of inflammatory bowel disease. It is a prodrug that is converted in the colon to 5-aminosalicylic acid (5-ASA), which exerts anti-inflammatory effects. The compound is a sodium salt of olsalazine, and its molecular structure features two 5-ASA molecules linked by an azo bond. Olsalazine sodium is typically administered orally and is known for its relatively low systemic absorption, which helps to minimize side effects. The compound is characterized by its solubility in water, which facilitates its absorption in the gastrointestinal tract. Common side effects may include gastrointestinal disturbances, such as diarrhea and abdominal pain. Due to its mechanism of action, olsalazine sodium is considered effective in maintaining remission in patients with ulcerative colitis. As with any medication, it is important for patients to consult healthcare professionals for appropriate usage and potential interactions with other drugs.

Formula: C₁₄H₁₀N₂O₆·2Na

InChI: InChI=1S/C14H10N2O6.2Na/c17-11-3-1-7(5-9(11)13(19)20)15-16-8-2-4-12(18)10(6-8)14(21)22;;/h1-6,17-18H,(H,19,20)(H,21,22);;

InChI key: InChIKey=WBFGLVPPGBVMLC-UHFFFAOYSA-N

SMILES: N(=NC1=CC(C(O)=O)=C(O)C=C1)C2=CC(C(O)=O)=C(O)C=C2.[Na]

Synonyms:

• 3,3′-Azobis[6-hydroxybenzoic acid] disodium salt
• Acid Chrome Flavine R
• Alizarol Flavine A
• Azodisal sodium
• Benzoic acid, 3,3′-(1,2-diazenediyl)bis[6-hydroxy-, sodium salt (1:2)
• Benzoic acid, 3,3′-azobis[6-hydroxy-, disodium salt
• Chromaven Yellow FA
• Chrome Fast Flavine A
• Chrome Fast Flavine J
• Chrome Yellow A extra
• Chrome Yellow AS
• Curolite Yellow 3R
• Diamond Chrome Yellow A ex
• Dipentum
• Disodium 3,3′-azobis(6-hydroxybenzoate)
• Disodium azodisalicylate
• Eriochromal Flavine A
• Eriochrome Flavine A
• Fenakrom Yellow 3G
• Metachrome Yellow A extra
• Monochrome Yellow A ex
• Mordant Yellow 5
• Nutrachrome Yellow NYA
• Olsalazine disodium
• Olsalazine sodium
• Omega Chrome Aurine GL
• Ph CJ 91B
• Pontachrome Flavine A
• Salicine Chrome Yellow A Extra
• Sodium azodisalicylate
• Solochrome Flavine G
• Synchromate Flavine A
• Telon Chrome Yellow T
• Tertrochrome Yellow A
• disodium 3,3'-(E)-diazene-1,2-diylbis(6-hydroxybenzoate)
• disodium 5-[(2Z)-2-(3-carboxylato-4-oxocyclohexa-2,5-dien-1-ylidene)hydrazino]-2-hydroxybenzoate
• C.I. 14130
• C.I. Mordant Yellow 5, disodium salt

OLSALAZINE SODIUM CRS

CAS: 6054-98-4

OLSALAZINE SODIUM CRS

Formula: C₁₄H₈N₂Na₂O₆

Molecular weight: 346.2027

Ref: 41-O0146000

OLSALAZINE SODIUM FOR PERFORMANCE TEST CRS

CAS: 6054-98-4

OLSALAZINE SODIUM FOR PERFORMANCE TEST CRS

Formula: C₁₄H₈N₂Na₂O₆

Molecular weight: 346.2027

Ref: 41-O0146010

Benzoic acid, 3,3'-azobis[6-hydroxy-, disodium salt

CAS: 6054-98-4

Formula: C₁₄H₈N₂Na₂O₆

Purity: 97%

Color and Shape: Solid

Molecular weight: 346.2027

Ref: IN-DA00IAPP

Olsalazine disodium

CAS: 6054-98-4

Olsalazine disodium (Dipentum) is bioconverted to 5-aminosalicylic acid (5-ASA) in the colon and has anti-inflammatory activity in ulcerative colitis.

Formula: C₁₄H₈N₂Na₂O₆

Purity: 99.47% - 99.52%

Color and Shape: Yellow Crystalline Powder

Molecular weight: 346.2

Ref: TM-T1544

Olsalazine Sodium

CAS: 6054-98-4

Olsalazine Sodium

Purity: 98%

Molecular weight: 346.2g/mol

Ref: 54-OR1029276

Olsalazine disodium

CAS: 6054-98-4

Olsalazine disodium

Purity: ≥98%

Molecular weight: 346.2g/mol

Ref: 54-BUP18087

Olsalazine Disodium Salt

CAS: 6054-98-4

Formula: C₁₄H₈N₂O₆·2Na

Molecular weight: 300.23 2*22.99

Ref: 4Z-O-221

Olsalazine Sodium

CAS: 15722-48-2, 6054-98-4

Formula: C₁₄H₈N₂Na₂O₆

Purity: >98.0%(HPLC)

Color and Shape: Light yellow to Brown powder to crystal

Molecular weight: 346.21

Ref: 3B-O0517

Olsalazine Sodium

Controlled Product

CAS: 6054-98-4

Formula: C₁₄H₈N₂O₆Na

Color and Shape: Neat

Molecular weight: 346.20

Ref: 86-MM1129.00

Olsalazine sodium salt

CAS: 6054-98-4

Olsalazine sodium salt is a drug that is used to treat bowel disease. It has been shown to be effective in treating ulcerative colitis and other hyperproliferative diseases, such as dermatitis herpetiformis, with the matrix effect of dextran sulfate. Olsalazine sodium salt is a combination therapy group drug that includes olsalazine, which is an anti-inflammatory drug, and dextran sulfate, which increases the surface area of the bowel and improves absorption. The chemiluminescence method was used to measure the cytosolic Ca2+ concentration in experimental models of colitis. The results showed that olsalazine sodium salt significantly reduced the level of cytosolic Ca2+, suggesting it may have anti-inflammatory properties.

Formula: C₁₄H₈N₂Na₂O₆

Purity: Min. 95%

Color and Shape: Yellow Powder

Molecular weight: 346.2 g/mol

Ref: 3D-FO26560

Olsalazine Sodium

CAS: 6054-98-4

Formula: C₁₄H₈N₂Na₂O₆

Purity: 95%

Color and Shape: Solid

Molecular weight: 346.206

Ref: 10-F448734

Olsalazine-13C12 Sodium Salt

Controlled Product

CAS: 6054-98-4

Applications Labelled Olsalazine (O586000). Dimer of Mesalazine (M258100), an anti-inflammatory drug used in the treatment of inflammatory bowel disease and ulcerative colitis.
References Willoughby, C.P., Gut, 23. 1081 (1982), Scand, J., et al.: Gastroenterol, 20, 607 (1985), Wadworth, A.N., et al.: Drugs, 41, 647 (1991)

Formula: C₂₁₃C₁₂H₈N₂Na₂O₆

Color and Shape: Neat

Molecular weight: 358.11

Ref: TR-O586002

Olsalazine Sodium

CAS: 6054-98-4

Color and Shape: Neat

Ref: 61-FOR1129.00