CAS 60547-97-9

2-(1-Piperazinyl)-4-amino-6,7-dimethoxyquinazoline

Description:

2-(1-Piperazinyl)-4-amino-6,7-dimethoxyquinazoline, with the CAS number 60547-97-9, is a chemical compound that belongs to the quinazoline class of heterocyclic compounds. It features a quinazoline core structure, which is characterized by a fused bicyclic system containing two nitrogen atoms. The presence of a piperazine moiety enhances its pharmacological properties, potentially contributing to its activity as a drug candidate. This compound typically exhibits moderate to high solubility in polar solvents, which is influenced by the methoxy groups and the piperazine ring. Its amino and methoxy substituents can participate in hydrogen bonding, affecting its interaction with biological targets. The compound may possess various biological activities, including potential antitumor or antimicrobial properties, making it of interest in medicinal chemistry. As with many quinazoline derivatives, it may also serve as a scaffold for the development of novel therapeutic agents. Proper handling and safety measures should be observed due to its chemical nature and potential biological effects.

Formula: C₁₄H₁₉N₅O₂

InChI: InChI=1S/C14H19N5O2/c1-20-11-7-9-10(8-12(11)21-2)17-14(18-13(9)15)19-5-3-16-4-6-19/h7-8,16H,3-6H2,1-2H3,(H2,15,17,18)

InChI key: InChIKey=APKHJGDGWQDBGM-UHFFFAOYSA-N

SMILES: NC=1C2=C(N=C(N1)N3CCNCC3)C=C(OC)C(OC)=C2

Synonyms:

• 2(1-Piperazinly)-4-amino-6,7-dimethoxyquinazoline
• 2-(1-Piperazinyl)-4-amino-6,7-dimethoxyquinazoline
• 2-(4-Piperazinyl)-4-amino-6,7-dimethoxyquinazoline
• 2-Piperazino-6,7-dimethoxy-4-quinazolinamine
• 4-Amino-2-(1-Piperazinyl)-6,7-Dimethoxy Quinazoline
• 4-Amino-2-(1-piperazinyl)-6,7-dimethoxyquinazoline
• 4-Amino-6,7-dimethoxy-2-(1-piperazinyl)quinazoline
• 4-Quinazolinamine, 6,7-dimethoxy-2-(1-piperazinyl)-
• 6,7-Dimethoxy-2-(1-piperazinyl)-4-quinazolinamine
• 6,7-Dimethoxy-2-(Piperazin-1-Yl)Quinazolin-4-Amine

2-piperazine-4-amino-6,7-dimethoxyquinazoline

CAS: 60547-97-9

Formula: C₁₄H₁₉N₅O₂

Color and Shape: Solid

Molecular weight: 289.3330

Ref: IN-DA00IAPS

Terazosin EP Impurity C (Terazosin USP Related Compound A (Free Form), Doxazosin EP Impurity G, Prazosin EP Impurity C)

CAS: 60547-97-9

Formula: C₁₄H₁₉N₅O₂

Color and Shape: White To Off-White Solid

Molecular weight: 289.34

Ref: 4Z-T-751

6,7-Dimethoxy-2-(piperazin-1-yl)quinazolin-4-amine

Controlled Product

CAS: 60547-97-9

Formula: C₁₄H₁₉N₅O₂

Color and Shape: Neat

Molecular weight: 289.33

Ref: 86-MM0085.01

4-Amino-6,7-dimethoxy-2-(piperazin-1-yl)quinazoline

CAS: 60547-97-9

4-Amino-6,7-dimethoxy-2-(piperazin-1-yl)quinazoline

Formula: C₁₄H₁₉N₅O₂

Purity: ≥95%

Color and Shape: white powder

Molecular weight: 289.33g/mol

Ref: 54-OR14899

Doxazosin EP Impurity G

CAS: 60547-97-9

Formula: C₁₄H₁₉N₅O₂

Molecular weight: 289.33

Ref: ST-EA-CP-D26007

2-Piperazinyl-4-amino-6,7-dimethoxyquinazoline

CAS: 60547-97-9

Impurity Terazosin EP Impurity C
Applications 2-Piperazinyl-4-amino-6,7-dimethoxyquinazoline (Terazosin EP Impurity C) is a metabolite of Prazosin. It is also an impurity arising in the synthesis of Terazosin (T105000).
References Bolognesi, M., et al.: J. Med. Chem., 44, 362 (2001), Shaw, Y., et al.: J. Med. Chem., 47, 4453 (2004), Erve, J., et al.: Drug Metab. Disposition, 35, 908 (2007), Cavalli, A., et al.: Bioorg. Med. Chem. Lett., 19, 3031 (2009),

Formula: C₁₄H₁₉N₅O₂

Color and Shape: White

Molecular weight: 289.33

Ref: TR-P480500

2-PADQZ

CAS: 60547-97-9

DPQ is an antiviral compound.

Formula: C₁₄H₁₉N₅O₂

Purity: 98%

Color and Shape: White Powder

Molecular weight: 289.33

Ref: TM-T19849

2-Piperazinyl-4-amino-6,7-dimethoxyquinazoline

CAS: 60547-97-9

2-Piperazinyl-4-amino-6,7-dimethoxyquinazoline (2PAQ) is a hypotensive agent that has been shown to be active against influenza virus in animal models. 2PAQ inhibits the replication of influenza virus by binding to viral RNA and preventing it from forming a single-stranded molecule. It also prevents the protein synthesis necessary for viral replication by binding to the RNP complex and inhibiting the transcription of viral RNA into DNA. 2PAQ is active against a broad range of viruses, including herpes simplex virus types 1 and 2, varicella zoster virus, cytomegalovirus, and rhinovirus. 2PAQ has been shown to inhibit cellular proliferation in vitro as well as blood pressure in vivo through its ability to inhibit nitric oxide synthase activity.

Formula: C₁₄H₁₉N₅O₂

Purity: Min. 95%

Molecular weight: 289.33 g/mol

Ref: 3D-FP27065

Terazosin EP Impurity C

CAS: 60547-97-9

Formula: C₁₄H₁₉N₅O₂

Molecular weight: 289.33

Ref: ST-EA-CP-T17003

Prazosin EP Impurity C

CAS: 60547-97-9

Formula: C₁₄H₁₉N₅O₂

Molecular weight: 289.33

Ref: ST-EA-CP-P28003