CAS 60548-08-5

4-Quinazolinamine, 6,7-dimethoxy-2-(1-piperazinyl)-, dihydrochloride

Description:

4-Quinazolinamine, 6,7-dimethoxy-2-(1-piperazinyl)-, dihydrochloride is a chemical compound characterized by its quinazoline core structure, which is a bicyclic compound containing a benzene ring fused to a pyrimidine ring. This particular derivative features two methoxy groups at the 6 and 7 positions, enhancing its solubility and potentially influencing its biological activity. The presence of a piperazine moiety at the 2-position contributes to its pharmacological properties, as piperazine derivatives are often associated with various therapeutic effects, including anxiolytic and antipsychotic activities. The dihydrochloride salt form indicates that the compound is stabilized by the addition of hydrochloric acid, which can improve its solubility in aqueous solutions, making it suitable for pharmaceutical applications. Overall, this compound is of interest in medicinal chemistry, particularly for its potential use in developing new therapeutic agents targeting various neurological and psychiatric disorders.

Formula: C₁₄H₁₉N₅O₂・2ClH

Terazosin Related Compound A (6,7-Dimethoxy-2-(piperazin-1-yl)quinazolin-4-amine dihydrochloride)

CAS: 60548-08-5

Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure, nesoi

Formula: C₁₄H₁₉N₅O₂·2HCl

Color and Shape: White Powder

Molecular weight: 289.15387

Ref: 45-1643463

6,7-Dimethoxy-2-(piperazin-1-yl)quinazolin-4-amine dihydrochloride

CAS: 60548-08-5

6,7-Dimethoxy-2-(piperazin-1-yl)quinazolin-4-amine dihydrochloride

Purity: 97%

Molecular weight: 362.26g/mol

Ref: 54-OR1075011

N-Des((tetrahydrofuran-2-yl)methanone)) Terazosin Dihydrochloride

Controlled Product

CAS: 60548-08-5

Applications N-Des((tetrahydrofuran-2-yl)methanone)) Terazosin Dihydrochloride is a related compound to Terazosin (T105000), a α-1-adrenergic blocker related to Prazosin (P702325).
References Patterson, S.E., et al.: J. Chromatog., 311, 206 (1984), Fort, F.L., et al.: Drug Chem. Toxicol., 7, 435 (1984), Lepor, H., et al.: J. Urol., 148, 1467 (1992),

Formula: C₁₄H₁₉N₅O₂HCl

Color and Shape: Neat

Molecular weight: 362.25

Ref: TR-D297940

6,7-Dimethoxy-2-(piperazin-1-yl)quinazolin-4-amine dihydrochloride

CAS: 60548-08-5

6,7-Dimethoxy-2-(piperazin-1-yl)quinazolin-4-amine dihydrochloride (DMPQ) is a piperazine derivative that is a potent and selective inhibitor of phosphodiesterase type 5 (PDE5). This drug has been shown to be useful in the treatment of the symptoms of benign prostatic hyperplasia. DMPQ inhibits the hydrolysis of cyclic adenosine monophosphate (cAMP), which leads to an increase in intracellular levels of cAMP. This drug also exhibits antihypertensive effects, as it inhibits the activity of nitric oxide synthase.

Formula: C₁₄H₂₁Cl₂N₅O₂

Purity: Min. 95%

Molecular weight: 362.3 g/mol

Ref: 3D-KCA54808