CAS 60560-33-0
:Pinacidil
Description:
Pinacidil is a chemical compound primarily recognized for its role as a potassium channel opener, which is utilized in the treatment of hypertension and certain types of angina. It is classified as a vasodilator, meaning it works by relaxing blood vessels, thereby improving blood flow and reducing blood pressure. The molecular structure of pinacidil includes a pyridine ring, which contributes to its pharmacological properties. It is typically administered in oral form and has a relatively long half-life, allowing for sustained therapeutic effects. Pinacidil is known to induce hyperpolarization of vascular smooth muscle cells, leading to vasodilation. Additionally, it may have effects on cardiac output and heart rate, although these can vary based on individual patient responses. As with any medication, pinacidil can have side effects, including headache, dizziness, and potential fluid retention, necessitating careful monitoring during treatment. Overall, pinacidil represents an important option in the management of cardiovascular conditions, particularly in patients who may not respond adequately to other antihypertensive therapies.
Formula:C13H19N5
InChI:InChI=1S/C13H19N5/c1-10(13(2,3)4)17-12(16-9-14)18-11-5-7-15-8-6-11/h5-8,10H,1-4H3,(H2,15,16,17,18)
InChI key:InChIKey=IVVNZDGDKPTYHK-UHFFFAOYSA-N
SMILES:C(=NC=1C=CN=CC1)(NC(C(C)(C)C)C)NC#N
Synonyms:- (?à)-Pinacidil
- (R,S)-Pinacidil
- 1-(3,3-Dimethylbutan-2-yl)-2-cyano-3-(pyridin-4-yl)guanidine
- N-Cyano-N′-4-pyridinyl-N′′-(1,2,2-trimethylpropyl)guanidine
- P 1134
- Pinacidil
- Pindac
- S 1230
- Guanidine, N-cyano-N′-4-pyridinyl-N′′-(1,2,2-trimethylpropyl)-
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Found 3 products.
Pinacidil
CAS:Pinacidil (P 1134) is a guanidine that opens potassium channels and directly dilates peripheral blood vessels in small arteries, lowering blood pressure andFormula:C13H19N5Purity:99.9%Color and Shape:SolidMolecular weight:245.32
