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CAS 60604-36-6

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(4R)-4-FLUORO-L-PROLINE HCL

Description:
(4R)-4-Fluoro-L-proline hydrochloride is a fluorinated derivative of the amino acid proline, characterized by the presence of a fluorine atom at the fourth carbon of the proline ring. This compound is typically encountered as a white to off-white crystalline solid and is soluble in water and other polar solvents, which is common for amino acids and their derivatives. The presence of the hydrochloride group enhances its solubility and stability. As a chiral molecule, it exists in specific stereoisomeric forms, with the (R) configuration being biologically relevant. This compound is of interest in pharmaceutical research, particularly in the development of peptide-based drugs and as a building block in organic synthesis. Its unique structural features may influence its biological activity, making it a subject of study in medicinal chemistry. Additionally, (4R)-4-fluoro-L-proline can serve as a useful tool in probing the roles of proline in protein structure and function due to the introduction of the fluorine atom, which can affect hydrogen bonding and steric interactions.
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