CAS 60607-34-3

Oxatomide

Description:

Oxatomide is a chemical compound classified as an antihistamine, primarily used for its sedative and anti-allergic properties. It is known for its ability to block histamine H1 receptors, which helps alleviate symptoms associated with allergic reactions, such as itching, sneezing, and runny nose. Oxatomide is typically administered in oral form and is recognized for its relatively low sedative effects compared to other antihistamines, making it a preferred choice in certain therapeutic contexts. The compound has a moderate solubility in water and is often formulated in various pharmaceutical preparations. Its chemical structure includes a piperidine ring, contributing to its pharmacological activity. As with many antihistamines, potential side effects may include drowsiness, dry mouth, and gastrointestinal disturbances. It is important to use Oxatomide under medical supervision, particularly in individuals with pre-existing health conditions or those taking other medications, to avoid adverse interactions. Overall, Oxatomide serves as a valuable option in the management of allergic conditions while maintaining a balance between efficacy and tolerability.

Formula: C₂₇H₃₀N₄O

InChI: InChI=1/C27H30N4O/c32-27-28-24-14-7-8-15-25(24)31(27)17-9-16-29-18-20-30(21-19-29)26(22-10-3-1-4-11-22)23-12-5-2-6-13-23/h1-8,10-15,26H,9,16-21H2,(H,28,32)

InChI key: InChIKey=BAINIUMDFURPJM-UHFFFAOYSA-N

SMILES: C(N1CCN(CCCN2C=3C(NC2=O)=CC=CC3)CC1)(C4=CC=CC=C4)C5=CC=CC=C5

Synonyms:

• 1-(3-(4-(Diphenylmethyl)-1-piperazinyl)propyl)-1,3-dihydro-2H-benzimidazol-2-one
• 1-(3-(4-(Diphenylmethyl)-1-piperazinyl)propyl)-2-benzimidazolinone
• 1-[3-(4-Benzhydrylpiperazin-1-ium-1-yl)propyl]benzimidazol-2-olate
• 1-[3-[4-(Diphenylmethyl)piperazin-1-ium-1-yl]propyl]-1H-benzimidazol-2-olate
• 1-{3-[4-(diphenylmethyl)piperazin-1-yl]propyl}-1,3-dihydro-2H-benzimidazol-2-one
• 2H-Benzimidazol-2-one, 1,3-dihydro-1-(3-(4-(diphenylmethyl)-1-piperazinyl)propyl)-
• 2H-Benzimidazol-2-one, 1-(3-(4-(diphenylmethyl)-1-piperazinyl)propyl)-1,3-dihydro-
• Brn 4724760
• Celtect
• Cobiona
• Dasten
• Kw-4354
• McN-JR 35443
• NSC 309710
• Oxatimide
• Oxatomida
• Oxatomida [INN-Spanish]
• Oxatomide [USAN:INN:BAN:JAN]
• Oxatomidum
• Oxatomidum [INN-Latin]
• Oxetal
• R 35443
• Tinset
• Unii-J31Il9Z2Ee
• Oxatomide
• KW-4354：McN-JR-35443
• 1-(3-(4-(diphenylmethyl)-1-piperazinyl)propyl)-1,3-dihydro-2h-benzimidazol-2
• Truxa
• Fensedyl
• r35443
• 2h-benzimidazol-2-one,1,3-dihydro-1-(3-(4-(diphenylmethyl)-1-piperazinyl)propy
• Cenacert
• 1-[3-[4-(Diphmylmethyl)-1-piperazirlyI]propyl]-1，3-dihydro-2H-benzimidazol-2one
• 1,3-dihydro-1-(3-(4-(diphenylmethyl)-1-piperazinyl)propyl)-2h-benzimidazol-2-on

Oxatomide

CAS: 60607-34-3

Color and Shape: Neat

Ref: 61-FOR1115.00

Oxatomide

CAS: 60607-34-3

Formula: C₂₇H₃₀N₄O

Molecular weight: 426.55

Ref: 7W-GP2150

Oxatomide

CAS: 60607-34-3

Oxatomide

Purity: ≥98%

Molecular weight: 426.55g/mol

Ref: 54-BUP12104

Oxatomide

CAS: 60607-34-3

Oxatomide: Dual H1/P2X7 antagonist, antihistamine, anti-allergic, treats immune diseases, IC50: 0.95 μM (P2X7), 0.43 μM (5-HT).

Formula: C₂₇H₃₀N₄O

Purity: 99.28% - 99.72%

Color and Shape: White Powder

Molecular weight: 426.55

Ref: TM-T19839

Oxatomide

CAS: 60607-34-3

Formula: C₂₇H₃₀N₄O

Color and Shape: Neat

Molecular weight: 426.55

Ref: 86-MM1115.00

Oxatomide

Controlled Product

CAS: 60607-34-3

Applications Orally active anti-allergic agent; related structurally to cinnarizine and having a novel biphasic mode of action.
References Richards, D.M., et al.: Drugs, 27, 210 (1984),

Formula: C₂₇H₃₀N₄O

Color and Shape: Neat

Molecular weight: 426.55

Ref: TR-O845100

Oxatomide

CAS: 60607-34-3

Oxatomide is a histamine 1 (H1) antagonist that is used to treat allergic symptoms and chronic cough. It has been shown to be effective in an experimental model of chronic pulmonary airway inflammation. Oxatomide may also have anti-inflammatory effects, but these have not been well studied. Oxatomide has also been shown to have clinical relevance for the treatment of some autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis.

Formula: C₂₇H₃₀N₄O

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 426.55 g/mol

Ref: 3D-FO26615

Oxatomide

CAS: 60607-34-3

Formula: C₂₇H₃₀N₄O

Molecular weight: 426.56

Ref: ST-EA-CP-C76011