CAS 60656-72-6

6-Chloro-2-(chloromethyl)-4-(2-fluorophenyl)-1,2-dihydroquinazoline 3-Oxide

Description:

6-Chloro-2-(chloromethyl)-4-(2-fluorophenyl)-1,2-dihydroquinazoline 3-oxide is a chemical compound characterized by its complex structure, which includes a quinazoline core with various substituents. The presence of chlorine and fluorine atoms contributes to its reactivity and potential biological activity. This compound typically exhibits properties such as moderate solubility in organic solvents and may have limited solubility in water due to its hydrophobic characteristics. The 3-oxide functional group suggests the presence of an oxygen atom bonded to the nitrogen in the quinazoline ring, which can influence its chemical reactivity and stability. Additionally, the chloromethyl group can serve as a site for further chemical modifications. Compounds of this nature are often studied for their potential pharmacological applications, including antimicrobial or anticancer activities, owing to the diverse biological properties associated with quinazoline derivatives. However, specific biological activity and toxicity profiles would require empirical investigation and are not universally defined.

Synonyms:

• 6-Chloro-2-(chloroMethyl)-4-(2-fluorophenyl)-1,2-dihydroquinazoline 3-Oxide
• Quinazoline, 6-chloro-2-(chloromethyl)-4-(2-fluorophenyl)-1,2-dihydro-, 3-oxide
• 6-Chloro-2-(chloroMethyl)-4-(2-fluorophenyl)-1,2-dihydroquinazoline 3-Oxide

Midazolam Impurity 28

CAS: 60656-72-6

Formula: C₁₅H₁₁Cl₂FN₂O

Molecular weight: 325.16

Ref: 4Z-M-255046

6-Chloro-2-(chloromethyl)-4-(2-fluorophenyl)-1,2-dihydroquinazoline 3-Oxide

Controlled Product

CAS: 60656-72-6

Applications 6-Chloro-2-(chloromethyl)-4-(2-fluorophenyl)-1,2-dihydroquinazoline 3-Oxide is an intermediate in the synthesis of the synthetic precursor of Midazolam (M343000), an anesthetic, anticonvulsant, sedative and hypotic agent.
References Laviana, L., et al.: J. Pharma. Biomed. Anal., 32, 167 (2003);

Formula: C₁₅H₁₁Cl₂FN₂O

Color and Shape: Neat

Molecular weight: 325.17

Ref: TR-C365840

Midazolam Impurity 13

CAS: 60656-72-6

Formula: C₁₅H₁₁Cl₂FN₂O

Molecular weight: 325.16

Ref: ST-EA-CP-M85032