CAS 60656-76-0

1H-1,4-Benzodiazepine, 7-chloro-5-(2-fluorophenyl)-2,3-dihydro-2-(nitromethylene)-, 4-oxide

Description:

1H-1,4-Benzodiazepine, 7-chloro-5-(2-fluorophenyl)-2,3-dihydro-2-(nitromethylene)-, 4-oxide, identified by CAS number 60656-76-0, is a chemical compound belonging to the benzodiazepine class, which is characterized by a fused benzene and diazepine ring structure. This specific compound features a chlorine atom at the 7-position and a 2-fluorophenyl group at the 5-position, contributing to its unique chemical properties. The presence of a nitromethylene group enhances its reactivity and potential biological activity. As a 4-oxide derivative, it may exhibit altered electronic properties compared to its non-oxidized counterparts. Benzodiazepines are often studied for their pharmacological effects, including anxiolytic, sedative, and anticonvulsant properties, although the specific biological activity of this compound would require further investigation. Its structural complexity suggests potential applications in medicinal chemistry, particularly in the development of new therapeutic agents. Safety and handling precautions are essential, as with all chemical substances, due to potential toxicity and reactivity.

Formula: C₁₆H₁₁ClFN₃O₃

InChI: InChI=1S/C16H11ClFN3O3/c17-10-5-6-15-13(7-10)16(12-3-1-2-4-14(12)18)20(22)8-11(19-15)9-21(23)24/h1-7,9,19H,8H2

InChI key: InChIKey=YFNLLWWUWXVJOM-UHFFFAOYSA-N

SMILES: O=N1=C(C=2C(NC(=CN(=O)=O)C1)=CC=C(Cl)C2)C3=C(F)C=CC=C3

Synonyms:

• 7-Chloro-1,3-dihydro-5-(2-fluorophenyl)-2-nitromethylene-2H-1,4-benzodiazepine-4-oxide
• 1H-1,4-Benzodiazepine, 7-chloro-5-(2-fluorophenyl)-2,3-dihydro-2-(nitromethylene)-, 4-oxide
• 7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-2-(nitromethylene)-1H-1,4-benzodiazepine 4-Oxide
• (E)-7-chloro-5-(2-fluorophenyl)-2-(nitromethylene)-2,3-dihydro-1H-benzo[e][1,4]diazepine 4-oxide
• 3-dihydro-5-(2-fluorophenyl)-2-nitromethylene-2H-1 ,4-benzodiazepine-
• 7-Chloro-1.3-dihydro-5-(2-fluorophenyl)-2-nitromethylene-2H-1 ,4-benzodiazepine-
• 1H-1,4-Benzodiazepine, 7-chloro-5-(2-fluorophenyl)-2,3-dihydro-2-(nitromethylene)-, 4-oxide
• 7-Chloro-1

7-Chloro-1,3-dihydro-5-(2-fluorophenyl)-2-nitromethylene-2H-1,4-benzodiazepine 4-Oxide

Controlled Product

CAS: 60656-76-0

Applications 7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-2-(nitromethylene)-1H-1,4-benzodiazepine 4-Oxide is the synthetic precursor of Midazolam (M343000), an anesthetic, anticonvulsant, sedative and hypotic agent.
References Laviana, L., et al.: J. Pharma. Biomed. Anal., 32, 167 (2003); Dundee, J. W., et al.: Drugs, 28, 519 (1984); Lahat, E., et al.: Br. Med. J., 321, 83 (2000)

Formula: C₁₆H₁₁ClFN₃O₃

Color and Shape: Neat

Molecular weight: 347.73

Ref: TR-C366465

Midazolam Nitromethylene Compound

CAS: 60656-76-0

Formula: C₁₆H₁₁ClFN₃O₃

Molecular weight: 347.73

Ref: ST-EA-CP-M85014