CAS 60696-52-8

2,5-Bis[1-(1,1-dimethyl-2-propen-1-yl)-1H-indol-3-yl]-3,6-dihydroxy-2,5-cyclohexadiene-1,4-dione

Description:

2,5-Bis[1-(1,1-dimethyl-2-propen-1-yl)-1H-indol-3-yl]-3,6-dihydroxy-2,5-cyclohexadiene-1,4-dione, with CAS number 60696-52-8, is a complex organic compound characterized by its unique structure that includes multiple functional groups. This substance features a cyclohexadiene core, which is substituted with hydroxyl groups and indole moieties, contributing to its potential biological activity. The presence of the dimethylallyl groups suggests that it may exhibit interesting reactivity and possibly serve as a precursor for further chemical modifications. The compound is likely to be soluble in organic solvents due to its hydrophobic indole components, while the hydroxyl groups may impart some degree of polarity. Its intricate structure may also indicate potential applications in pharmaceuticals or as a dye, although specific applications would depend on further research into its properties and behavior in various environments. Overall, this compound exemplifies the complexity often found in organic chemistry, particularly in the realm of natural product synthesis and medicinal chemistry.

Formula: C₃₂H₃₀N₂O₄

InChI: InChI=1/C32H30N2O4/c1-7-31(3,4)33-17-21(19-13-9-11-15-23(19)33)25-27(35)29(37)26(30(38)28(25)36)22-18-34(32(5,6)8-2)24-16-12-10-14-20(22)24/h7-18,35,38H,1-2H2,3-6H3

InChI key: InChIKey=KMHWTYMNRHJTQG-UHFFFAOYSA-N

SMILES: O=C1C(C=2C=3C(N(C(C=C)(C)C)C2)=CC=CC3)=C(O)C(=O)C(=C1O)C=4C=5C(N(C(C=C)(C)C)C4)=CC=CC5

Synonyms:

• 2,5-Cyclohexadiene-1,4-dione, 2,5-bis[1-(1,1-dimethyl-2-propenyl)-1H-indol-3-yl]-3,6-dihydroxy-
• Asterriquinone
• 2,5-Bis[1-(1,1-dimethyl-2-propen-1-yl)-1H-indol-3-yl]-3,6-dihydroxy-2,5-cyclohexadiene-1,4-dione
• 2,5-cyclohexadiene-1,4-dione, 2,5-bis[1-(1,1-dimethyl-2-propen-1-yl)-1H-indol-3-yl]-3,6-dihydroxy-
• 2,5-Cyclohexadiene-1,4-dione, 2,5-bis(1-(1,1-dimethyl-2-propenyl)-1H-indol-3-yl)-3,6-dihydroxy-
• 2,5-Cyclohexadiene-1,4-dione, 2,5-bis[1-(1,1-dimethyl-2-propenyl)-1H-indol-3-yl]-3,6-dihydroxy-
• 2,5-Cyclohexadiene-1,4-dione, 2,5-bis[1-(1,1-dimethyl-2-propen-1-yl)-1H-indol-3-yl]-3,6-dihydroxy-
• Demethylasterriquinone A1
• Asterriquinone SU5504

Asterriquinone

CAS: 60696-52-8

Asterriquinone (ARQ) is an analog of Asterriquinone and a Grb-2 binding inhibitor. It hinders the interaction between Grb-2 and tyrosine-phosphorylated EGFR, with an IC50 of 8.37 μM. Additionally, Asterriquinone serves as an HIV1 reverse transcriptase inhibitor, with a Ki of 2.3 μM, and it also inhibits the binding activities of Grb-7 and PLC-γ.

Formula: C₃₂H₃₀N₂O₄

Color and Shape: Solid

Molecular weight: 506.592

Ref: TM-TN9103