CAS 60696-62-0

3-[(3R,5S,7R,10S,12S,13R,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]butanoic acid

Description:

The chemical substance known as "3-[(3R,5S,7R,10S,12S,13R,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]butanoic acid," with the CAS number 60696-62-0, is a complex organic compound characterized by its steroid-like structure. It features multiple hydroxyl (-OH) groups, which contribute to its hydrophilicity and potential biological activity. The presence of a butanoic acid moiety indicates that it has carboxylic acid functionality, which can participate in various chemical reactions, including esterification and acid-base reactions. The stereochemistry of the molecule, denoted by the specific R and S configurations, suggests that it may exhibit chiral properties, influencing its interactions in biological systems. This compound may be of interest in medicinal chemistry and pharmacology due to its structural similarity to steroid hormones, potentially impacting its biological activity and therapeutic applications. Overall, its complex structure and functional groups suggest a range of possible interactions and uses in biochemical contexts.

Formula: C₂₃H₃₈O₅

InChI: InChI=1/C23H38O5/c1-12(8-20(27)28)15-4-5-16-21-17(11-19(26)23(15,16)3)22(2)7-6-14(24)9-13(22)10-18(21)25/h12-19,21,24-26H,4-11H2,1-3H3,(H,27,28)/t12?,13-,14+,15+,16?,17?,18+,19-,21?,22-,23+/m0/s1

Norcholic Acid

CAS: 60696-62-0

Norcholic Acid (Nor Cholic Acid) is a bile acid that is efficiently absorbed by the intestine and rapidly secreted into the bile.

Formula: C₂₃H₃₈O₅

Purity: 98.79% - 99.17%

Color and Shape: Solid

Molecular weight: 394.54

Ref: TM-T37177

Nor Cholic Acid

Controlled Product

CAS: 60696-62-0

Applications A novel bile acid, an analogue of Cholic acid (C432600).
References Yamaga, N., et al.: J. Biochem., 116, 1123 (1994),

Formula: C₂₃H₃₈O₅

Color and Shape: Neat

Molecular weight: 394.54

Ref: TR-N661440

Nor cholic acid

Controlled Product

CAS: 60696-62-0

Norcholic acid is an amide type of bile acid that is synthesized in the liver. Norcholic acid has been shown to be effective in treating cirrhosis and its associated symptoms, such as fatigue, nausea, and weight loss. Norcholic acid is converted to hydroxylated metabolites by the liver and excreted into the urine or faeces. The effective dose of norcholic acid for treating cirrhosis has been determined through a study with t84 cells. The detergent compositions used in this study were Triton X-100, Tween 20, and Brij 35. This study also found that udca therapy was more effective than norcholic acid alone for treating cirrhosis. A biological sample (urine) from patients with chronic liver disease showed elevated concentrations of norcholic acid when compared to healthy individuals. Additionally, Caco-2 cells have been shown to metabolize norcholic acid into products that inhibit tumor

Formula: C₂₃H₃₈O₅

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 394.54 g/mol

Ref: 3D-FN26404

Nor Cholic Acid

CAS: 60696-62-0

Formula: C₂₃H₃₈O₅

Molecular weight: 394.54

Ref: ST-EA-CP-C93039