CAS 607-68-1

2,4-Dichloroquinazoline

Description:

2,4-Dichloroquinazoline is a heterocyclic organic compound characterized by its quinazoline structure, which consists of a fused benzene and pyrimidine ring. It features two chlorine substituents at the 2 and 4 positions of the quinazoline ring, contributing to its chemical reactivity and potential applications. This compound is typically a crystalline solid and is known for its role in various chemical syntheses and as an intermediate in the production of pharmaceuticals and agrochemicals. Its molecular formula reflects the presence of carbon, hydrogen, nitrogen, and chlorine atoms, indicating its potential for diverse chemical interactions. 2,4-Dichloroquinazoline may exhibit biological activity, making it of interest in medicinal chemistry, particularly in the development of compounds with antitumor or antimicrobial properties. As with many halogenated compounds, it is essential to handle it with care due to potential toxicity and environmental impact. Proper safety measures should be observed when working with this substance in laboratory settings.

Formula: C₈H₄Cl₂N₂

InChI: InChI=1S/C8H4Cl2N2/c9-7-5-3-1-2-4-6(5)11-8(10)12-7/h1-4H

InChI key: InChIKey=TUQSVSYUEBNNKQ-UHFFFAOYSA-N

SMILES: ClC=1C2=C(N=C(Cl)N1)C=CC=C2

Synonyms:

• 2,4-Dichloroquinazol
• 5-(4-Methoxyphenyl)-1,3-Oxazole
• Iflab-Bb F2108-0057
• NSC 75192
• Quinazoline, 2,4-Dichloro-
• Quinazoline,2,4-Dichloro-6,7-Dimethoxy-
• 2,4-Dichloroquinazoline

2,4-Dichloroquinazoline

CAS: 607-68-1

Formula: C₈H₄Cl₂N₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 199.0368

Ref: IN-DA0032ZB

2,4-Dichloroquinazoline

CAS: 607-68-1

2,4-Dichloroquinazoline

Formula: C₈H₄Cl₂N₂

Purity: 98%

Color and Shape: yellow powder

Molecular weight: 199.04g/mol

Ref: 54-OR52131

2,4-Dichloroquinazoline

CAS: 607-68-1

Formula: C₈H₄Cl₂N₂

Purity: 95%

Color and Shape: Solid, Crystalline Powder

Molecular weight: 199.03

Ref: 10-F047662

2,4-Dichloroquinazoline

Controlled Product

CAS: 607-68-1

Applications 2,4-Dichloroquinazoline has been used as a reactant for the preparation of 1-methyl-1H-imidazole derivatives as Jak2 inhibitors.
References Su, Q., et. al.: J. Med. Chem., 57, 144 (2014)

Formula: C₈H₄Cl₂N₂

Color and Shape: Neat

Molecular weight: 199.037

Ref: TR-D436290

2,4-Dichloroquinazoline

CAS: 607-68-1

2,4-Dichloroquinazoline is a synthetic compound that has been used to study the interaction of dopamine with the D4 receptor. It is an efficient method for synthesizing alkylthio compounds and can be used in synthesis of amines. 2,4-Dichloroquinazoline binds to the d4 receptor and inhibits binding of dopamine to the receptor by competitive inhibition. The chlorine atom is responsible for this binding. This compound also reacts with phosphorus pentachloride to form an alkylthio chloride, which has been shown to be effective against Trichomonas vaginalis.

Formula: C₈H₄Cl₂N₂

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 199.04 g/mol

Ref: 3D-FD40770