CAS 60736-70-1

Benzofenac

Description:

Benzofenac, with the CAS number 60736-70-1, is a chemical compound primarily recognized for its application as a non-steroidal anti-inflammatory drug (NSAID). It exhibits analgesic and anti-inflammatory properties, making it useful in the treatment of pain and inflammation. Benzofenac is characterized by its ability to inhibit cyclooxygenase (COX) enzymes, which play a crucial role in the synthesis of prostaglandins, mediators of inflammation and pain. The compound typically appears as a white to off-white crystalline powder and is soluble in organic solvents but has limited solubility in water. Its molecular structure includes a benzophenone moiety, contributing to its pharmacological activity. In terms of safety, like many NSAIDs, benzofenac may have side effects, including gastrointestinal discomfort and potential cardiovascular risks, necessitating careful consideration in therapeutic use. Overall, benzofenac represents a significant compound in the realm of anti-inflammatory medications, with ongoing research into its efficacy and safety profile.

Formula: C₁₅H₁₃ClO₃

InChI: InChI=1S/C15H13ClO3/c16-13-8-12(9-15(17)18)6-7-14(13)19-10-11-4-2-1-3-5-11/h1-8H,9-10H2,(H,17,18)

InChI key: InChIKey=DFHBBMJTBBLQSA-UHFFFAOYSA-N

SMILES: C(C(O)=O)C1=CC(Cl)=C(OCC2=CC=CC=C2)C=C1

Synonyms:

• Benzofenac
• Benzeneacetic acid, 3-chloro-4-(phenylmethoxy)-
• VUFB 9682
• 3-Chloro-4-(phenylmethoxy)benzeneacetic acid
• 3-Chloro-4-(benzyloxy)phenylacetic acid