CAS 607373-82-0

4-methoxy-5-nitro-pyridin-2-ol

Description:

4-Methoxy-5-nitro-pyridin-2-ol is an organic compound characterized by its pyridine ring, which is substituted with a methoxy group and a nitro group, along with a hydroxyl group. The presence of the methoxy group (-OCH3) enhances its solubility in organic solvents, while the nitro group (-NO2) contributes to its reactivity and potential as a nitrating agent. The hydroxyl group (-OH) provides the compound with polar characteristics, making it capable of engaging in hydrogen bonding. This compound may exhibit biological activity, making it of interest in pharmaceutical research. Its molecular structure suggests potential applications in medicinal chemistry, particularly in the development of new therapeutic agents. Additionally, the compound's stability and reactivity can be influenced by the electronic effects of the substituents on the pyridine ring. As with many nitro-containing compounds, care should be taken regarding its handling and storage due to potential toxicity and environmental impact.

Formula: C₆H₆N₂O₄

InChI: InChI=1/C6H6N2O4/c1-12-5-2-6(9)7-3-4(5)8(10)11/h2-3H,1H3,(H,7,9)

SMILES: COc1cc(ncc1N(=O)=O)O

Synonyms:

• 2-Pyridinol, 4-methoxy-5-nitro-
• 4-Methoxy-5-nitropyridin-2-ol

5-NITRO-2-HYDROXY-4-METHOXYPYRIDINE

CAS: 607373-82-0

Formula: C₆H₆N₂O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 170.1228

Ref: IN-DA00EACU

2-Hydroxy-4-methoxy-5-nitropyridine

CAS: 607373-82-0

2-Hydroxy-4-methoxy-5-nitropyridine

Formula: C₆H₆N₂O₄

Purity: ≥95%

Color and Shape: Solid

Molecular weight: 170.12g/mol

Ref: 54-OR14756

4-Methoxy-5-nitropyridin-2(1H)-one

CAS: 607373-82-0

Purity: 95.0%

Molecular weight: 170.12399291992188

Ref: 10-F236696

4-Methoxy-5-nitro-1H-pyridin-2-one

Controlled Product

CAS: 607373-82-0

Applications 2-Hydroxy-methoxy-5-nitropyridine is used in the preparation of Rho-Kinase inhibitors that display antihypertensive activity. Also it is used in the preparation of aminofurans as potent inhibitors of AKT kinase.
References Rouse, M. et al.: Bioorg, Med. Chem. Lett., 19, 1508 (2009); Stavenger, R. et al.: J. Med. Chem., 50, 2 (2007);

Formula: C₆H₆N₂O₄

Color and Shape: Neat

Molecular weight: 170.12

Ref: TR-M262735