Minigastrin is a peptide hormone that plays a crucial role in the regulation of gastric acid secretion and gastrointestinal motility. It is a derivative of gastrin, specifically consisting of a shorter chain of amino acids, typically comprising 14 residues. Minigastrin primarily stimulates the parietal cells in the stomach to secrete hydrochloric acid, thereby facilitating digestion. It is also involved in promoting the growth of gastric mucosa and enhancing the motility of the gastrointestinal tract. The substance is characterized by its ability to bind to the cholecystokinin B (CCK-B) receptor, which is essential for its biological activity. Minigastrin is often studied in the context of gastrointestinal disorders and is of interest in both clinical and research settings. Its CAS number, 60748-07-4, is used for identification in chemical databases. As a peptide, it is sensitive to degradation by proteolytic enzymes, which can affect its stability and bioavailability in therapeutic applications.

Minigastrin

60748-07-4: Minigastrin is a peptide hormone that plays a crucial role in the regulation of gastric acid secretion and gastrointestinal motility. It is a derivative of gastrin, specifically consisting of a shorter chain of amino acids, typically comprising 14 residues. Minigastrin primarily stimulates the parietal cells in the stomach to secrete hydrochloric acid, thereby facilitating digestion. It is also involved in promoting the growth of gastric mucosa and enhancing the motility of the gastrointestinal tract. The substance is characterized by its ability to bind to the cholecystokinin B (CCK-B) receptor, which is essential for its biological activity. Minigastrin is often studied in the context of gastrointestinal disorders and is of interest in both clinical and research settings. Its CAS number, 60748-07-4, is used for identification in chemical databases. As a peptide, it is sensitive to degradation by proteolytic enzymes, which can affect its stability and bioavailability in therapeutic applications.

HG-13, LEEEEEAYGWMDF-amide, has been isolated from tumor tissue. The peptide corresponds to the fragment 5-17 of human gastrin I.

Minigastrin I (human)

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CAS 60748-07-4

Minigastrin

Minigastrin I (human)

Ref: 01-4011601

Minigastrin I tifluoroacetic acid

Ref: 3D-FM108882