CAS 607742-69-8

Intepirdine

Description:

Intepirdine, with the CAS number 607742-69-8, is a chemical compound that has been investigated primarily for its potential therapeutic applications, particularly in the treatment of cognitive disorders such as Alzheimer's disease. It functions as a selective antagonist of the 5-HT6 serotonin receptor, which is implicated in various neurological processes, including cognition and memory. Intepirdine is characterized by its ability to enhance neurotransmitter release, potentially improving synaptic function. The compound has undergone various phases of clinical trials to assess its efficacy and safety profile. Its chemical structure includes specific functional groups that contribute to its pharmacological activity, although detailed structural information is typically found in specialized chemical databases. As with many investigational drugs, the full spectrum of its pharmacodynamics, pharmacokinetics, and side effects is still being explored, making it a subject of ongoing research in the field of medicinal chemistry and neuropharmacology.

Formula: C₁₉H₁₉N₃O₂S

InChI: InChI=1S/C19H19N3O2S/c23-25(24,16-6-2-1-3-7-16)17-13-15-5-4-8-18(19(15)21-14-17)22-11-9-20-10-12-22/h1-8,13-14,20H,9-12H2

InChI key: InChIKey=JJZFWROHYSMCMU-UHFFFAOYSA-N

SMILES: S(=O)(=O)(C1=CC2=C(C(=CC=C2)N3CCNCC3)N=C1)C4=CC=CC=C4

Synonyms:

• 3-(Phenylsulfonyl)-8-(1-piperazinyl)quinoline
• SB 742457
• Quinoline, 3-(phenylsulfonyl)-8-(1-piperazinyl)-
• GSK 742457
• 3-Phenylsulfonyl-8-(piperazin-1-yl)quinoline

Quinoline, 3-(phenylsulfonyl)-8-(1-piperazinyl)-

CAS: 607742-69-8

Formula: C₁₉H₁₉N₃O₂S

Purity: %

Color and Shape: Solid

Molecular weight: 353.4381

Ref: IN-DA00ECEM

Intepirdine

CAS: 607742-69-8

Intepirdine

Purity: ≥95%

Molecular weight: 353.44g/mol

Ref: 54-BUP15402

3-(Phenylsulfonyl)-8-(Piperazin-1-Yl)Quinoline

CAS: 607742-69-8

3-(Phenylsulfonyl)-8-(Piperazin-1-Yl)Quinoline

Purity: 98%

Molecular weight: 353.44g/mol

Ref: 54-OR1024260

Intepirdine

CAS: 607742-69-8

Intepirdine (GSK-742457) is a highly selective 5-HT6 receptor antagonist, used in trials studying the treatment of Alzheimer's Disease.

Formula: C₁₉H₁₉N₃O₂S

Purity: 98% - 98.63%

Color and Shape: Solid

Molecular weight: 353.44

Ref: TM-T1774

Intepirdine

CAS: 607742-69-8

Intepirdine is a compound that belongs to the class of quinoline derivatives. It has been shown to be an effective dose in clinical studies and is used as a treatment for Alzheimer's disease. Intepirdine binds to 5-HT2A receptors, which are involved in the serotonergic system and are located in the hippocampal formation. It has also been shown to be protonated at nitrogen atoms, which may cause it to have a different pharmacological profile than other molecules in its class. Intepirdine is currently undergoing phase II clinical trials for use as a treatment for Parkinson's disease.

Formula: C₁₉H₁₉N₃O₂S

Purity: Min. 95%

Molecular weight: 353.44 g/mol

Ref: 3D-HZA74269