CAS 608-05-9

5-Methylisatin

Description:

5-Methylisatin, with the CAS number 608-05-9, is an organic compound belonging to the class of isatins, which are derived from indole. It features a methyl group at the 5-position of the isatin structure, which contributes to its unique chemical properties. This compound typically appears as a yellow to orange crystalline solid and is known for its potential biological activities, including antimicrobial and anticancer properties. 5-Methylisatin is soluble in organic solvents such as ethanol and dimethyl sulfoxide, but its solubility in water is limited. The compound can undergo various chemical reactions, including oxidation and substitution, making it a valuable intermediate in organic synthesis. Its structure includes a carbonyl group and an amine, which can participate in further chemical transformations. Due to its interesting properties, 5-Methylisatin is of interest in medicinal chemistry and material science, where it may be explored for developing new therapeutic agents or functional materials.

Formula: C₉H₇NO₂

InChI: InChI=1S/C9H7NO2/c1-5-2-3-7-6(4-5)8(11)9(12)10-7/h2-4H,1H3,(H,10,11,12)

InChI key: InChIKey=VAJCSPZKMVQIAP-UHFFFAOYSA-N

SMILES: O=C1C=2C(NC1=O)=CC=C(C)C2

Synonyms:

• 1H-Indole-2,3-dione, 5-methyl-
• 5-Methyl-2,3-dihydro-2,3-dioxoindole
• 5-Methyl-2,3-indolinedione
• 5-Methylindole-2,3-dione
• 5-methyl-1H-indole-2,3-dione
• 5-methylindole-2,3(1H)-dione
• Indole-2,3-dione, 5-methyl-
• Isatin, 5-methyl-
• NSC 9398
• 5-Methylisatin

5-Methylisatin

CAS: 608-05-9

Formula: C₉H₇NO₂

Purity: >99.0%(GC)

Color and Shape: Orange to Amber to Dark red powder to crystal

Molecular weight: 161.16

Ref: 3B-M1703

5-Methylisatin, 97%

CAS: 608-05-9

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₉H₇NO₂

Purity: 97%

Color and Shape: Crystals or powder or crystalline powder or lumps or clear liquid as melt, Colorless to dark red to red to dark brown to brown

Molecular weight: 161.16

Ref: 02-L08009

5-Methylindoline-2,3-dione

CAS: 608-05-9

Formula: C₉H₇NO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 161.1574

Ref: IN-DA003MW7

5-Methylisatin

CAS: 608-05-9

Formula: C₉H₇NO₂

Molecular weight: 161.16

Ref: 7W-GK8285

5-Methylisatin

CAS: 608-05-9

5-Methylisatin

Purity: 98%

Color and Shape: Solid

Molecular weight: 161.16g/mol

Ref: 54-OR30934

5-Methylisatin

CAS: 608-05-9

5-Methylisatin is a reaction rate-limiting substrate in the conversion of pyridoxal 5'-phosphate to pyridoxamine 5'-phosphate. It is oxidized by hydroxyl radicals to form malonic acid and anhydrous acetonitrile. The reaction is catalyzed by an enzyme called tissue nonspecific alkaline phosphatase (TNAP). TNAP activity can be inhibited by test compounds, such as anthranilic acid and homogenates, which are substances that contain enzymes or cells from tissues. Hydroxyl groups on the 5-methylisatin molecule form hydrogen bonds with the nitrogen atoms of TNAP, which causes a conformational change in the enzyme. This change inhibits its ability to react with other substrates, resulting in decreased levels of 5-methylisatin and increased levels of pyridoxal 5'-phosphate. The inhibition can be reversed by adding hydroxide ions or increasing

Formula: C₉H₇NO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 161.16 g/mol

Ref: 3D-FM38396

5-Methylindoline-2,3-dione

CAS: 608-05-9

Formula: C₉H₇NO₂

Purity: 97%

Color and Shape: Solid, Red to brown powder or crystals

Molecular weight: 161.16

Ref: 10-F093452