CAS 6080-33-7
:Sinomenine hydrochloride
Description:
Sinomenine hydrochloride is a chemical compound derived from the plant Sinomenium acutum, which is traditionally used in Chinese medicine. It is classified as an alkaloid and exhibits various pharmacological properties, including anti-inflammatory, analgesic, and immunomodulatory effects. The compound is typically presented as a white to off-white crystalline powder, which is soluble in water and exhibits a slightly bitter taste. Sinomenine hydrochloride interacts with multiple biological pathways, making it of interest for research in treating conditions such as rheumatoid arthritis and other inflammatory diseases. Its mechanism of action involves modulation of immune responses and inhibition of pro-inflammatory cytokines. Additionally, the compound has been studied for its potential neuroprotective effects. As with many alkaloids, safety and efficacy profiles are essential for clinical applications, and ongoing research continues to explore its therapeutic potential and side effects. Proper handling and storage conditions are necessary to maintain its stability and effectiveness in pharmaceutical formulations.
Formula:C19H23NO4·ClH
InChI:InChI=1S/C19H23NO4.ClH/c1-20-7-6-19-10-14(21)16(24-3)9-12(19)13(20)8-11-4-5-15(23-2)18(22)17(11)19;/h4-5,9,12-13,22H,6-8,10H2,1-3H3;1H/t12-,13+,19-;/m1./s1
InChI key:InChIKey=YMEVIMJAUHZFMW-VUIDNZEBSA-N
SMILES:OC1=C2[C@]34[C@@]([C@](CC2=CC=C1OC)(N(C)CC3)[H])(C=C(OC)C(=O)C4)[H].Cl
Synonyms:- (9Alpha,13Alpha,14Alpha)-4-Hydroxy-3,7-Dimethoxy-17-Methyl-7,8-Didehydromorphinan-17-Ium-6-One Chloride
- 4-Hydroxy-3,7-Dimethoxy-17-Methyl-7,8-Didehydromorphinan-6-One
- 9α,13α,14α-Morphinan-6-one, 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-, hydrochloride
- Cucoline, hydrochloride
- Morphinan-6-one, 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-, hydrochloride (1:1), (9α,13α,14α)-
- Morphinan-6-one, 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-, hydrochloride, (9α,13α,14α)-
- NSC 76021
- Sinomenin hydrochloride
- Sinomenine HCL
- See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 12 products.
Sinomenine (hydrochloride)
CAS:Formula:C19H24ClNO4Purity:98%Color and Shape:SolidMolecular weight:365.8512Sinomenine hydrochloride
CAS:<p>Sinomenine hydrochloride (Kukoline hydrochloride) is extracted from Sinomenium Acutum Rehderett Wilson.</p>Formula:C19H24ClNO4Purity:99.43%Color and Shape:SolidMolecular weight:365.851Sinomenine hydrochloride
CAS:Formula:C19H23NO4·HCl·xH2OPurity:≥ 98.0%Color and Shape:White to off-white or beige crystalline powderMolecular weight:365.85 (anhydrous)Sinomenine Hydrochloride
CAS:Controlled ProductFormula:C19H23NO4·ClHColor and Shape:NeatMolecular weight:365.85Sinomenine hydrochloride
CAS:Natural alkaloidFormula:C19H23NO4HClPurity:≥ 98.0 % (HPLC)Color and Shape:PowderMolecular weight:365.86Sinomenine Hydrochloride
CAS:Controlled Product<p>Applications Sinomenine is an optical isomer of Methoxythebainone. Sinomenine was extracted from root of Sinomenium acutum. Sinomenine has anti-inflammatory and analgesic effect.<br>References Kitasato, O., et al.: Arch. Exp. Med., 6, 259 (1925), Lodge, D., et al.: Eur. J. Pharmacol., 26, 277 (1974),<br></p>Formula:C19H23NO4·ClHColor and Shape:WhiteMolecular weight:365.85Sinomenine hydrochloride
CAS:Formula:C19H24ClNO4Purity:99%Color and Shape:SolidMolecular weight:365.85Sinomenine HCl
CAS:Controlled Product<p>Sinomenine HCl is an alkaloid compound, which is an extract derived from the Chinese medicinal plant Sinomenium acutum. It functions primarily through its anti-inflammatory and immunomodulatory actions. Sinomenine HCl exerts its effects by inhibiting the activation of nuclear factor kappa B (NF-κB) and suppressing the production of pro-inflammatory cytokines. Additionally, it acts on opioid receptors, contributing to its analgesic properties.</p>Formula:C19H23NO4·HClPurity:Min. 98 Area-%Color and Shape:White Off-White PowderMolecular weight:365.85 g/mol
