CAS 608137-32-2

Lisdexamfetamine

Description:

Lisdexamfetamine is a prodrug of dextroamphetamine, primarily used in the treatment of attention deficit hyperactivity disorder (ADHD) and binge eating disorder. It is classified as a central nervous system stimulant. The chemical structure of lisdexamfetamine consists of a lysine molecule covalently bonded to dextroamphetamine, which allows for a gradual release of the active drug upon metabolism. This characteristic contributes to its extended duration of action and reduced potential for abuse compared to other stimulants. Lisdexamfetamine is typically administered orally and is known for its relatively favorable side effect profile, although common side effects may include decreased appetite, insomnia, and dry mouth. The substance is metabolized in the body to release dextroamphetamine, which then exerts its therapeutic effects by increasing the levels of neurotransmitters such as dopamine and norepinephrine in the brain. Due to its stimulant properties, lisdexamfetamine is classified as a controlled substance in many jurisdictions.

Formula: C₁₅H₂₅N₃O

InChI: InChI=1S/C15H25N3O/c1-12(11-13-7-3-2-4-8-13)18-15(19)14(17)9-5-6-10-16/h2-4,7-8,12,14H,5-6,9-11,16-17H2,1H3,(H,18,19)/t12-,14-/m0/s1

InChI key: InChIKey=VOBHXZCDAVEXEY-JSGCOSHPSA-N

SMILES: C([C@@H](NC([C@H](CCCCN)N)=O)C)C1=CC=CC=C1

Synonyms:

• Lisdexamfetamine
• Lisdexamphetamine
• (2S)-2,6-Diamino-N-[(1S)-1-methyl-2-phenylethyl]hexanamide
• N-[(1S)-1-Methyl-2-phenylethyl]-L-lysinamide
• Hexanamide, 2,6-diamino-N-[(1S)-1-methyl-2-phenylethyl]-, (2S)-

Lisdexamfetamine dimesylate

Controlled Product

CAS: 608137-32-2

Dopamine uptake inhibitor; treats ADHD

Formula: C₁₅H₂₅N₃O·2CH₄O₃S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 455.59 g/mol

Ref: 3D-FL162437

Lisdexamphetamine Dihydrochloride (1mg/ml in Methanol)

Controlled Product

CAS: 608137-32-2, 914480-48-1

Formula: C₁₅H₂₅N₃O

Color and Shape: Single Solution

Molecular weight: 263.378

Ref: TR-KIT2555

Lisdexamphetamine-d3 Dimesylate (1mg/ml (as free base) in Methanol)

Controlled Product

CAS: 608137-32-2, 608137-33-3

Formula: C₁₅H₂₂D₃N₃O·CH₄O₃S

Color and Shape: Single Solution

Molecular weight: 362.5

Ref: TR-KIT1810