CAS 60851-34-5

2,3,4,6,7,8-Hexachlorodibenzofuran

Description:

2,3,4,6,7,8-Hexachlorodibenzofuran (CAS 60851-34-5) is a chlorinated organic compound belonging to the dibenzofuran family, characterized by the presence of six chlorine atoms substituted at specific positions on the dibenzofuran structure. This compound is a persistent environmental pollutant, often associated with industrial processes and waste incineration. It exhibits high lipophilicity, leading to bioaccumulation in living organisms and potential biomagnification in food chains. 2,3,4,6,7,8-Hexachlorodibenzofuran is known for its toxicity, with potential adverse effects on human health and ecosystems, including endocrine disruption and carcinogenic properties. Its stability and resistance to degradation contribute to its persistence in the environment, raising concerns regarding its long-term ecological impact. Regulatory measures are in place in various regions to monitor and limit exposure to such compounds due to their hazardous nature. Overall, the characteristics of this substance underscore the importance of environmental management and remediation efforts to mitigate its effects.

Formula: C₁₂H₂Cl₆O

InChI: InChI=1S/C12H2Cl6O/c13-5-1-3-4-2-6(14)8(16)10(18)12(4)19-11(3)9(17)7(5)15/h1-2H

InChI key: InChIKey=XTAHLACQOVXINQ-UHFFFAOYSA-N

SMILES: ClC1=C2C(C=3C(O2)=C(Cl)C(Cl)=C(Cl)C3)=CC(Cl)=C1Cl

Synonyms:

• Dibenzofuran, 2,3,4,6,7,8-Hexachloro-
• 2,3,4,6,7,8-Hexachlorodibenzofuran
• 2,3,4,6,7,8-HxCDF
• F 130
• Pcdf 130
• 2,3,4,6,7,8-Hexachlorodibenzo[b,d]furan

2,3,4,6,7,8-Hexachlorodibenzofuran

CAS: 60851-34-5

2,3,4,6,7,8-Hexachlorodibenzofuran (2,3,4,6,7,8-HxCDF) is a type of polychlorinated dibenzofuran (PCDF). It induces the expression of aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin-o-deethylase (EROD) genes in H-4-II-E rat hepatoma cells, with EC50 values of 0.687 and 0.575 nM, respectively.

Formula: C₁₂H₂Cl₆O

Color and Shape: Solid

Molecular weight: 374.86

Ref: TM-T203593

2,3,4,6,7,8-Hexachlorodibenzofuran

CAS: 60851-34-5

Formula: C₁₂H₂Cl₆O

Molecular weight: 374.87

Ref: 4Z-B-104009

2,3,4,6,7,8-Hexachlorodibenzofuran

CAS: 60851-34-5

Applications 2,3,4,6,7,8-Hexachlorodibenzofuran, is a toxic polychlorinated dibenzofurans (PCDD/F), detected in domestic meat and poultry. It can be used as purified standards for analytical, toxic, and biological studies of these environmental contaminants.
References Huwe, J., et al.: Food Addit. Contam., 21, 182 (2004), Llobet, J., et al.: Toxicol. Lett., 178, 117 (2008); Feil, V., et al.: J. Agric. Food Chem., 48, 6163 (2000); Safe, S. H., et al.: J. Agric. Food Chem., 32, 68 (1984);

Formula: C₁₂H₂Cl₆O

Color and Shape: Neat

Molecular weight: 374.86

Ref: TR-H265105