CAS 60881-76-7

(22R)-22-hydroxycholest-4-en-3-one

Description:

(22R)-22-hydroxycholest-4-en-3-one, with the CAS number 60881-76-7, is a steroid compound that plays a significant role in various biological processes. It is a derivative of cholesterol, characterized by the presence of a hydroxyl group at the 22nd carbon position and a double bond between the 4th and 5th carbons in its steroid structure. This compound is typically found in biological systems and is involved in the biosynthesis of steroid hormones. Its stereochemistry, indicated by the (22R) designation, suggests a specific three-dimensional arrangement of atoms that can influence its biological activity and interactions with enzymes and receptors. The presence of the ketone group at the 3-position further contributes to its reactivity and potential metabolic pathways. As a steroid, it is lipophilic, allowing it to easily integrate into cellular membranes and participate in signaling pathways. Understanding its characteristics is crucial for research in biochemistry, pharmacology, and the development of therapeutic agents targeting steroid-related pathways.

Formula: C₂₇H₄₄O₂

InChI: InChI=1/C27H44O2/c1-17(2)6-11-25(29)18(3)22-9-10-23-21-8-7-19-16-20(28)12-14-26(19,4)24(21)13-15-27(22,23)5/h16-18,21-25,29H,6-15H2,1-5H3/t18-,21-,22+,23-,24-,25+,26-,27+/m0/s1

Synonyms:

• Cholest-4-en-3-one, 22-hydroxy-, (22R)-

22-Hydroxycholest-4-en-3-one

Controlled Product

CAS: 60881-76-7

Formula: C₂₇H₄₄O₂

Color and Shape: Neat

Molecular weight: 400.64

Ref: TR-H951035

22-Hydroxycholest-4-en-3-one

Controlled Product

CAS: 60881-76-7

22-Hydroxycholest-4-en-3-one is an analog that has been shown to have potent anticancer activity. It works by inhibiting kinase activity, which plays a key role in the regulation of cell cycle and apoptosis. This inhibitor has been found to induce apoptosis in cancer cells, leading to tumor regression. 22-Hydroxycholest-4-en-3-one has also been shown to inhibit protein synthesis and inhibit the growth of human cancer cell lines. In Chinese medicine, it is used for its medicinal properties and is present in urine as a natural metabolite. Its potential as an anticancer agent makes it a promising candidate for further research and development of cancer therapies.

Formula: C₂₇H₄₄O₂

Purity: Min. 95%

Molecular weight: 400.6 g/mol

Ref: 3D-KCA88176