CAS 60902-28-5

Acetamide-2,2,2-d3,N-(4-hydroxyphenyl)- (9CI)

Description:

Acetamide-2,2,2-d3,N-(4-hydroxyphenyl)-, with the CAS number 60902-28-5, is a deuterated derivative of acetamide, which is an amide of acetic acid. This compound features a hydroxyphenyl group, indicating the presence of a phenolic structure that contributes to its chemical properties. The deuteration at the methyl group (2,2,2-d3) enhances its utility in various analytical techniques, particularly in nuclear magnetic resonance (NMR) spectroscopy, where it can provide insights into molecular dynamics and interactions. Acetamide derivatives are often used in pharmaceuticals and biochemical research due to their ability to participate in hydrogen bonding and their relatively low toxicity. The hydroxy group on the phenyl ring can also influence the compound's solubility and reactivity, making it a valuable compound in organic synthesis and medicinal chemistry. Overall, this compound exemplifies the intersection of organic chemistry and analytical applications, particularly in the study of biological systems and drug development.

Formula: C₈H₆D₃NO₂

Synonyms:

• N-(4-Hydroxyphenyl)Acetamide-2,2,2-D3
• Acetaminophen-D3
• N-(4-Hydroxypentyl)acetamide-2,2,2-D3
• (Acetminophen

Acetaminophen-d3 (Paracetamol-d3)

CAS: 60902-28-5

Formula: C₈H₆D₃NO₂

Color and Shape: Off-White Solid

Molecular weight: 154.18

Ref: 4Z-A-021

N-(4-Hydroxyphenyl)acetamide-2,2,2-d3

CAS: 60902-28-5

Formula: HOC₆H₄NHCOCD₃

Purity: 98 atom % D

Color and Shape: White To Brown Solid

Molecular weight: 154.08216

Ref: 3U-D6324

Paracetamol D3 (methyl D3)

Controlled Product

CAS: 60902-28-5

Formula: C₈H₃H₆NO₂

Color and Shape: Neat

Molecular weight: 154.18

Ref: 04-C15846100

Acetaminophen-d3

Controlled Product

CAS: 60902-28-5

Applications Acetaminophen-d3 is deuterium labeled Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).
References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)

Formula: C₈₂H₃H₆NO₂

Color and Shape: White

Molecular weight: 154.18

Ref: TR-A161221