CAS 609799-22-6

Tasimelteon

Description:

Tasimelteon is a synthetic compound primarily recognized for its role as a melatonin receptor agonist, specifically targeting the MT1 and MT2 receptors. It is classified as a non-benzodiazepine sleep aid and is primarily used in the treatment of circadian rhythm sleep disorders, particularly in individuals who are blind and experience non-24-hour sleep-wake disorder. The molecular formula of Tasimelteon reflects its complex structure, which includes multiple functional groups that contribute to its pharmacological activity. The substance is typically administered orally and has a relatively short half-life, necessitating careful dosing to achieve desired therapeutic effects. Its efficacy is attributed to its ability to mimic the action of melatonin, a hormone that regulates sleep-wake cycles. Additionally, Tasimelteon has undergone various clinical trials to assess its safety and effectiveness, demonstrating a favorable profile for managing sleep-related issues without the sedative side effects commonly associated with traditional sleep medications. As with any pharmacological agent, potential side effects and contraindications should be considered when prescribing Tasimelteon.

Formula: C₁₅H₁₉NO₂

InChI: InChI=1S/C15H19NO2/c1-2-15(17)16-9-10-8-13(10)11-4-3-5-14-12(11)6-7-18-14/h3-5,10,13H,2,6-9H2,1H3,(H,16,17)/t10-,13+/m0/s1

InChI key: InChIKey=PTOIAAWZLUQTIO-GXFFZTMASA-N

SMILES: C(NC(CC)=O)[C@H]1[C@@H](C1)C2=C3C(=CC=C2)OCC3

Synonyms:

• (1R-trans)-N-[[2-(2,3-Dihydro-4-benzofuranyl)cyclopropyl]methyl]propanamide
• Bms 214778
• Hetlioz
• N-[[(1R,2R)-2-(2,3-Dihydro-4-benzofuranyl)cyclopropyl]methyl]propanamide
• N-{[(1R,2R)-2-(2,3-dihydro-1-benzofuran-4-yl)cyclopropyl]methyl}propanamide
• Propanamide, N-[[(1R,2R)-2-(2,3-dihydro-4-benzofuranyl)cyclopropyl]methyl]-
• Vec 162
• MA 1

Tasimelteon

CAS: 609799-22-6

Formula: C₁₅H₁₉NO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 245.3169

Ref: IN-DA00ECGF

Tasimelteon

CAS: 609799-22-6

Tasimelteon

Purity: ≥98%

Molecular weight: 245.32g/mol

Ref: 54-BUP11183

Tasimelteon

CAS: 609799-22-6

Formula: C₁₅H₁₉NO₂

Color and Shape: Off-White Solid

Molecular weight: 245.32

Ref: 4Z-T-224001

Tasimelteon

CAS: 609799-22-6

Formula: C₁₅H₁₉NO₂

Purity: >95.0%(qNMR)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 245.32

Ref: 3B-T3813

Tasimelteon

CAS: 609799-22-6

Tasimelteon (BMS-214778) is a melatonin receptor agonist that is used for the treatment of non-24 hour sleep-wake disorder in blind individuals.

Formula: C₁₅H₁₉NO₂

Purity: 98.93% - 99.93%

Color and Shape: Solid

Molecular weight: 245.32

Ref: TM-T3495

Tasimelteon

CAS: 609799-22-6

Applications Tasimelteon is a novel drug, used in the treatment of non-24 hour sleep-wake disorder. It helps to correct the circadian rhythm disorder often seen in patients who are visually impaired.
References Lahon, J. et al.: World. J. Pharm. Res., 3, 1521 (2014);

Formula: C₁₅H₁₉NO₂

Color and Shape: Neat

Molecular weight: 245.3169

Ref: TR-T007740