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CAS 609807-25-2

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(3-fluoro-5-methoxyphenyl)boronic acid

Description:
(3-Fluoro-5-methoxyphenyl)boronic acid is an organoboron compound characterized by the presence of a boronic acid functional group attached to a phenyl ring that has both a fluorine and a methoxy substituent. This compound typically exhibits a white to off-white crystalline appearance and is soluble in polar solvents such as water and alcohols, owing to the boronic acid group, which can form hydrogen bonds. The presence of the fluorine atom can influence the electronic properties of the molecule, potentially enhancing its reactivity in various chemical reactions, including Suzuki coupling, which is a common method for forming carbon-carbon bonds. The methoxy group can also serve as an electron-donating substituent, affecting the compound's reactivity and stability. Additionally, boronic acids are known for their ability to form reversible complexes with diols, making them useful in various applications, including drug development and materials science. Overall, (3-fluoro-5-methoxyphenyl)boronic acid is a versatile compound with significant utility in organic synthesis and medicinal chemistry.
Formula:C7H8BFO3
InChI:InChI=1/C7H8BFO3/c1-12-7-3-5(8(10)11)2-6(9)4-7/h2-4,10-11H,1H3
SMILES:COc1cc(cc(c1)F)B(O)O
Synonyms:
  • Boronic acid, B-(3-fluoro-5-methoxyphenyl)-
  • 3-Fluoro-5-Methoxyphenylboronic Acid
  • 3-Fluoro-5-methoxybenzeneboronic acid
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