CAS 61-56-3

Sulthiame

Description:

Sulthiame, with the CAS number 61-56-3, is a sulfonamide derivative primarily used as an anticonvulsant medication. It is characterized by its ability to inhibit carbonic anhydrase, which plays a role in regulating acid-base balance in the body. This compound is typically presented as a white to off-white crystalline powder, and it is soluble in water, making it suitable for various pharmaceutical formulations. Sulthiame is known for its effectiveness in managing certain types of epilepsy, particularly in children. Its mechanism of action involves modulating neurotransmitter release and stabilizing neuronal membranes, which helps to reduce seizure activity. While generally well-tolerated, potential side effects may include allergic reactions, gastrointestinal disturbances, and hematological changes. As with any medication, it is essential to monitor patients for adverse effects and adjust dosages accordingly. Overall, sulthiame represents a valuable option in the therapeutic arsenal for epilepsy management, particularly in cases where other treatments may not be effective.

Formula: C₁₀H₁₄N₂O₄S₂

InChI: InChI=1S/C10H14N2O4S2/c11-18(15,16)10-5-3-9(4-6-10)12-7-1-2-8-17(12,13)14/h3-6H,1-2,7-8H2,(H2,11,15,16)

InChI key: InChIKey=HMHVCUVYZFYAJI-UHFFFAOYSA-N

SMILES: O=S1(=O)N(C2=CC=C(S(N)(=O)=O)C=C2)CCCC1

Synonyms:

• 2-(p-Sulfamoylphenyl)-tetrahydro-2H-1,2-thiazine 1,1-dioxide
• 2H-1,2-Thiazine, 2-[4-(aminosulfonyl)phenyl]tetrahydro-, 1,1-dioxide
• 2H-1,2-Thiazine, benzenesulfonamide deriv.
• 2H-1,2-Thiazine, tetrahydro-2-p-sulfamoylphenyl-, 1,1-dioxide
• 4-(1,1-Dioxido-1,2-Thiazinan-2-Yl)Benzenesulfonamide
• 4-(Tetrahydro-1,1-dioxido-2H-1,2-thiazin-2-yl)benzenesulfonamide
• 4-(perhydro-1,2-thiazin-2-yl)benzenesulphonamide S,S-dioxide
• A 168
• A 168 (anticonvulsant)
• Bayer A 168
• Benzenesulfonamide, 4-(tetrahydro-1,1-dioxido-2H-1,2-thiazin-2-yl)-
• Benzenesulfonamide, 4-(tetrahydro-2H-1,2-thiazin-2-yl)-, S,S-dioxide
• Benzenesulfonamide, p-(tetrahydro-2H-1,2-thiazin-2-yl)-, S,S-dioxide
• Benzenesulfonamide, p-(tetrahydro-2H-1,2-thiazin-2-yl)-, dioxide
• Conadil
• Contravul
• Elisal
• Ospolot
• Riker 594
• Sulphenyltame
• Sulphenytame
• Sulphthiame
• Sulthiam
• Sulthiame
• Sulthiamine
• Sultiam
• Trolone

Sultiame

CAS: 61-56-3

Color and Shape: Neat

Ref: 61-FOR1155.00

sultiame

CAS: 61-56-3

Formula: C₁₀H₁₄N₂O₄S₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 290.3592

Ref: IN-DA00EBXR

Sultiame

CAS: 61-56-3

Sultiame

Purity: ≥98%

Molecular weight: 290.36g/mol

Ref: 54-BUP12802

Sultiame 100 µg/mL in Acetonitrile

CAS: 61-56-3

Formula: C₁₀H₁₄N₂O₄S₂

Color and Shape: Single Solution

Molecular weight: 290.36

Ref: 04-A17039000AL-100

Sultiame

Controlled Product

CAS: 61-56-3

Formula: C₁₀H₁₄N₂O₄S₂

Color and Shape: Neat

Molecular weight: 290.36

Ref: 86-MM1155.00

Sulthiame

CAS: 61-56-3

Formula: C₁₀H₁₄N₂O₄S₂

Molecular weight: 290.35

Ref: 4Z-S-196001

Sulthiame

Controlled Product

CAS: 61-56-3

Applications Sulthiame is a benzenesulfonamide derivative. Sulthiame acts as an inhibitor of the enzyme carbonic anhydrase. Sulthiame is used as an anticonvulsant in the treatment of benign and symptomatic focal epilepsy.
References Green, J. et al.: Antiepilep. Drugs, 744 (1972); Inui, M.: Seish. Shin. Zas., 71, 114 (1969); Leniger, T. et al.: Epilepsia, 43, 469 (2002);

Formula: C₁₀H₁₄N₂O₄S₂

Color and Shape: Off White Solid

Molecular weight: 290.36

Ref: TR-S789500

sultiame

CAS: 61-56-3

Purity: 99%

Molecular weight: 290.3500061

Ref: 10-F866588

4-(5-Hydroxy-1,1-dioxido-1,2-thiazinan-2-yl)benzenesulfonamide

Controlled Product

CAS: 61-56-3

Formula: C₁₀H₁₄N₂O₅S₂

Color and Shape: Neat

Molecular weight: 306.35

Ref: TR-H402120

Sultiame

CAS: 61-56-3

Sultiame is an inhibitor of carbonic anhydrase. Sultiame can be used in antiepileptic research.

Formula: C₁₀H₁₄N₂O₄S₂

Purity: 99.91%

Color and Shape: Solid

Molecular weight: 290.36

Ref: TM-T16960

Sultiame

CAS: 61-56-3

Formula: C₁₀H₁₄N₂O₄S₂

Color and Shape: Neat

Molecular weight: 290.36

Ref: 04-C17039000