CAS 61-70-1

1-Methyl-1,3-dihydroindol-2-one

Description:

1-Methyl-1,3-dihydroindol-2-one, also known as indolin-2-one, is an organic compound characterized by its bicyclic structure, which consists of a fused indole and a carbonyl group. This compound typically appears as a white to off-white solid and is soluble in organic solvents such as ethanol and dimethyl sulfoxide, but has limited solubility in water. It features a methyl group at the nitrogen atom of the indole ring, which influences its reactivity and biological activity. 1-Methyl-1,3-dihydroindol-2-one is of interest in various fields, including medicinal chemistry, due to its potential pharmacological properties, such as anti-inflammatory and anticancer activities. The compound can undergo various chemical reactions, including oxidation and substitution, making it a versatile intermediate in organic synthesis. Its stability and reactivity can be affected by environmental conditions, such as pH and temperature. Overall, 1-Methyl-1,3-dihydroindol-2-one serves as an important building block in the development of novel therapeutic agents.

Formula: C₉H₉NO

InChI: InChI=1S/C9H9NO/c1-10-8-5-3-2-4-7(8)6-9(10)11/h2-5H,6H2,1H3

InChI key: InChIKey=RSQUAQMIGSMNNE-UHFFFAOYSA-N

SMILES: CN1C=2C(CC1=O)=CC=CC2

Synonyms:

• 1,3-Dihydro-1-methyl-2H-indol-2-one
• 1-Methyl-1,3-dihydroindol-2-one
• 1-Methyl-1H-indolin-2-one
• 1-Methyl-2,3-dihydro-1H-indol-2-one
• 1-Methyl-2-Indolinone
• 1-Methyl-2-indolone
• 1-Methyl-2-oxindole
• 1-Methyl-3H-indol-2-one
• 1-Methylindol-2(3H)-one
• 1-Methyloxindole
• 2-Indolinone, 1-methyl-
• 2H-indol-2-one, 1,3-dihydro-1-methyl-
• Ba 2777
• N-Methyl-2-indolinone
• N-Methyl-2-oxindole
• N-Methylindol-2(3H)-one
• N-Methyloxindole
• NSC 97219
• Oxindole, 1-methyl-

1-Methyl-2-indolinone

CAS: 61-70-1

Formula: C₉H₉NO

Purity: 98%

Color and Shape: Solid

Molecular weight: 147.1739

Ref: IN-DA0032SU

1-Methyl-2-oxindole

CAS: 61-70-1

1-Methyl-2-oxindole

Formula: C₉H₉NO

Purity: 95%

Color and Shape: white to pink solid

Molecular weight: 147.17g/mol

Ref: 54-OR27652

1-Methylindolin-2-one

CAS: 61-70-1

Formula: C₉H₉NO

Purity: 95%

Color and Shape: Solid

Molecular weight: 147.177

Ref: 10-F340047

1-Methyl-2-oxindole (1-Methyl-2-indolone)

CAS: 61-70-1

Applications 1-Methyl-2-indolone is a reactant for preparation of fluorescent analogues of strigolactones as affectors of parasitic weed germination and fungal branching, irreversible Nek2 Kinase Inhibitors and anticancer agents.
References Prandi, C., et al.: Eur. J. Org. Chem., 3781, Henise, J., et al.: J. Med. Chem., 54, 4133 (2011); Kamal, A., et al.: Eur. J. Med. Chem., 46, 2427 (2011)

Formula: C₉H₉NO

Color and Shape: Solid

Molecular weight: 147.174

Ref: TR-M305490

1-Methylindolin-2-one

CAS: 61-70-1

1-Methylindolin-2-one is an enolate that is synthetically prepared from a methoxymethyl group. 1-Methylindolin-2-one has the ability to inhibit bacterial growth by inhibiting the synthesis of proteins and nucleic acids. It binds to the carbonyl group on the bacteria surface, which prevents the formation of reactive compounds which are necessary for cell division. The reactive form of 1-methylindolin-2-one also has antibacterial activity against a variety of bacteria such as Pseudomonas aeruginosa, Staphylococcus aureus, and Escherichia coli.

Formula: C₉H₉NO

Purity: Min. 95%

Molecular weight: 147.18 g/mol

Ref: 3D-AAA06170