CymitQuimica logo

CAS 61-72-3

:

Cloxacillin

Description:
Cloxacillin is a semisynthetic penicillin antibiotic that is primarily used to treat infections caused by penicillinase-producing staphylococci. It is characterized by its beta-lactam structure, which is essential for its antibacterial activity. Cloxacillin is effective against a range of Gram-positive bacteria, particularly Staphylococcus aureus, and is resistant to degradation by certain beta-lactamases, making it a valuable option in treating resistant infections. The compound is typically administered orally or intravenously and is known for its relatively low toxicity profile. Its pharmacokinetics include good absorption from the gastrointestinal tract, although food can affect its bioavailability. Cloxacillin is metabolized in the liver and excreted primarily through the kidneys. Common side effects may include gastrointestinal disturbances, allergic reactions, and, in rare cases, more severe effects such as liver toxicity. As with all antibiotics, it is crucial to use cloxacillin judiciously to prevent the development of antibiotic resistance.
Formula:C19H18ClN3O5S
InChI:InChI=1S/C19H18ClN3O5S/c1-8-11(12(22-28-8)9-6-4-5-7-10(9)20)15(24)21-13-16(25)23-14(18(26)27)19(2,3)29-17(13)23/h4-7,13-14,17H,1-3H3,(H,21,24)(H,26,27)/t13-,14+,17-/m1/s1
InChI key:InChIKey=LQOLIRLGBULYKD-JKIFEVAISA-N
SMILES:N(C(=O)C=1C(=NOC1C)C2=C(Cl)C=CC=C2)[C@H]3[C@@]4(N([C@@H](C(O)=O)C(C)(C)S4)C3=O)[H]
Synonyms:
  • (2S,5R,6R)-6-({[3-(2-chlorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
  • (2S,5R,6R)-6-[[[3-(2-Chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
  • (3-(o-Chlorophenyl)-5-methyl-4-isoxazolyl)penicillin
  • 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((3-(2-chlorophenyl)-5-methyl-4-isoxazolyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta))-
  • 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(3-(O-chlorophenyl)-5-methyl-4-isoxazolecarboxamido)-3,3-dimethyl-7-oxo-
  • 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(3-(o-chlorophenyl)-S-methyl-4-isoxazolecarboxamido)-3,3-dimethyl-7-oxo-
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimet hyl-7-oxo-, (2S,5R,6R)-
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-, (2S,5R,6R)-
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-, [2S-(2α,5α,6β)]-
  • 6-(((3-(2-Chlorophenyl)-5-methyl-4-isoxazolyl)carbonyl)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid
  • See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 5 products.
  • Cloxacillin Sodium Salt Monohydrate
    TCI
    + Info

    Cloxacillin Sodium Salt Monohydrate

    CAS:
    Formula:C19H17ClN3NaO5S·H2O
    Purity:>98.0%(HPLC)
    Color and Shape:White to Orange to Green powder to crystaline
    Molecular weight:475.88

    Ref: 3B-C2244

    1g
    47.00€
    5g
    138.00€
  • Cloxacillin 1000 µg/mL in Acetonitrile
    Doctor Ehrenstorfer
    + Info

    Cloxacillin 1000 µg/mL in Acetonitrile

    Controlled Product
    CAS:
    Formula:C19H18ClN3O5S
    Color and Shape:Single Solution
    Molecular weight:435.8813

    Ref: 04-A11692090AL-1000

    1ml
    37.00€
  • Cloxacillin
    Targetmol
    + Info

    Cloxacillin

    CAS:
    <p>Cloxacillin, a β-lactamase inhibitor, tackles S. aureus inflammation and has an IC50 of 0.04 µM.</p>
    Formula:C19H18ClN3O5S
    Color and Shape:Solid
    Molecular weight:435.88

    Ref: TM-T73058

  • Cloxacilline-13c4
    Biosynth
    + Info

    Cloxacilline-13c4

    CAS:
    <p>Cloxacillin is a sulfa drug that inhibits bacterial growth by binding to the 50S ribosomal subunit. It inhibits the synthesis of bacterial cell walls by binding to dextran sulfate and polymerase chain. Cloxacillin has been shown to have experimental solubility data in various biological samples, such as human serum and wastewater treatment. Cloxacillin has also been shown to be effective against Streptococcus pyogenes (Group A streptococci) and Staphylococcus aureus, which are two common causes of infectious diseases. Cloxacillin may be used in combination with vancomycin therapy or benzalkonium chloride for these infections.</p>
    Formula:C19H18ClN3O5S
    Purity:Min. 95%
    Molecular weight:435.88 g/mol

    Ref: 3D-FC175020

    ne
    To inquire
  • Oxacillin EP Impurity E
    Standalix
    + Info

    Oxacillin EP Impurity E

    CAS:
    Formula:C19H18ClN3O5S
    Molecular weight:435.88

    Ref: ST-EA-CP-O58005

    10mg
    To inquire
    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire