CAS 61-80-3

Zoxazolamine

Description:

Zoxazolamine is a chemical compound classified as a muscle relaxant and is primarily used in the treatment of muscle spasms and related conditions. It belongs to the class of compounds known as oxazoles, characterized by a five-membered heterocyclic ring containing both nitrogen and oxygen atoms. Zoxazolamine exhibits a range of pharmacological effects, including central nervous system depressant activity, which contributes to its muscle-relaxing properties. The compound is typically administered in a clinical setting and may be associated with side effects such as drowsiness, dizziness, and gastrointestinal disturbances. Its mechanism of action involves the inhibition of neuronal excitability, leading to reduced muscle tone. Zoxazolamine is also notable for its relatively low solubility in water, which can influence its bioavailability and therapeutic efficacy. As with many pharmaceuticals, careful consideration of dosage and potential interactions with other medications is essential for safe use. Overall, Zoxazolamine serves as an important agent in the management of musculoskeletal disorders.

Formula: C₇H₅ClN₂O

InChI: InChI=1/C7H5ClN2O/c8-4-1-2-6-5(3-4)10-7(9)11-6/h1-3H,(H2,9,10)

InChI key: InChIKey=YGCODSQDUUUKIV-UHFFFAOYSA-N

SMILES: NC=1OC=2C(N1)=CC(Cl)=CC2

Synonyms:

• 2-Benzoxazolamine, 5-chloro-
• 5-Chloro-1,3-Benzoxazol-2-Amine
• 5-Chloro-2-aminobenzoxazole
• 5-Chloro-2-benzoxazolamine
• 5-Chlorobenzo[d]oxazol-2-amine
• 5-Chlorobenzoxazol-2-Ylamine
• 5-Chlorobenzoxazol-2-amine
• Benzoxazole, 2-amino-5-chloro-
• Deflexol
• Flexilon
• Flexin
• McN-485
• NSC 24995
• Zoxamin
• Zoxazolamine
• Zoxine
• 2-Amino-5-chlorobenzoxazole
• 2-amino-5-chloro-benzoxazol
• Contrazole
• TIMTEC-BB SBB003874
• usafma-12

Zoxazolamine

CAS: 61-80-3

Zoxazolamine (NSC-24995) is a uricosuric and muscle relaxant.

Formula: C₇H₅ClN₂O

Purity: 99.54%

Color and Shape: Light Brown To Yellow-Brown Powder

Molecular weight: 168.58

Ref: TM-T0922

5-CHLOROBENZO[D]OXAZOL-2-AMINE

CAS: 61-80-3

Formula: C₇H₅ClN₂O

Purity: 95%

Color and Shape: Solid

Molecular weight: 168.5804

Ref: IN-DA003MOH

Zoxazolamine

CAS: 61-80-3

Zoxazolamine

Purity: ≥98%

Molecular weight: 168.58g/mol

Ref: 54-BUP17379

5-Chlorobenzo[d]oxazol-2-amine

CAS: 61-80-3

Formula: C₇H₅ClN₂O

Purity: >98.0%(T)(qNMR)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 168.58

Ref: 3B-Z0068

2-Amino-5-Chlorobenzoxazole

CAS: 61-80-3

Formula: C₇H₅ClN₂O

Molecular weight: 168.58

Ref: 4Z-B-139263

2-Amino-5-chlorobenzoxazole

CAS: 61-80-3

2-Amino-5-chlorobenzoxazole

Formula: C₇H₅ClN₂O

Purity: 98%

Color and Shape: off-white solid

Molecular weight: 168.58g/mol

Ref: 54-OR963716

2-Amino-5-chlorobenzoxazole (Zoxazolamine)

Controlled Product

CAS: 61-80-3

Applications Centrally acting myorelaxant; formerly used as an antispasmodic and uricosuric. Used as a tool for assessing hepatic cytochrome P-450 activity in rodents.
References Tomaszeski, J.E., et al.: Arch. Biochem. Biophys., 176, 788 (1976), M van der Graaff, et al.: Drug Metab. Dispos., 14, 331 (1986),

Formula: C₇H₅ClN₂O

Color and Shape: Neat

Molecular weight: 168.58

Ref: TR-Z700950

Zoxazolamine

CAS: 61-80-3

Zoxazolamine is a synthetic, immunosuppressive and cytotoxic agent that inhibits the enzyme activities of cytosolic Ca2+-ATPases. It has been shown to suppress antibody response in rats. Zoxazolamine also has a number of drug interactions, including inhibition of tetracycline metabolism and induction of cytochrome P450 enzymes. The experimental model for zoxazolamine is based on the T84 cell line, which is an intestinal epithelial cell line derived from human ileum. Zoxazolamine has been shown to induce toxicity in this cell line. Zoxazolamine also causes release of bile acids from rat liver microsomes and can lead to autoimmune diseases in experimental models.

Formula: C₇H₅ClN₂O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 168.58 g/mol

Ref: 3D-FZ28790

2-Amino-5-chlorobenzoxazole

CAS: 61-80-3

Formula: C₇H₅ClN₂O

Purity: 95%

Color and Shape: Brown powder

Molecular weight: 168.58

Ref: 10-F001002