CAS 610-97-9

Methyl 2-iodobenzoate

Description:

Methyl 2-iodobenzoate is an organic compound with the molecular formula C9H9IO2. It is classified as an aryl halide, specifically a substituted benzoate ester. This compound features a methyl ester group (-COOCH3) attached to a benzene ring that is further substituted with an iodine atom at the ortho position relative to the ester group. Methyl 2-iodobenzoate is typically a colorless to pale yellow liquid with a characteristic aromatic odor. It is soluble in organic solvents such as ethanol and ether but has limited solubility in water due to its hydrophobic aromatic structure. The presence of the iodine atom makes it a useful reagent in organic synthesis, particularly in nucleophilic substitution reactions. Additionally, it can serve as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. Safety precautions should be taken when handling this compound, as it may pose health risks if inhaled or ingested, and appropriate protective equipment should be used.

Formula: C₈H₇IO₂

InChI: InChI=1S/C8H7IO2/c1-11-8(10)6-4-2-3-5-7(6)9/h2-5H,1H3

InChI key: InChIKey=BXXLTVBTDZXPTN-UHFFFAOYSA-N

SMILES: C(OC)(=O)C1=C(I)C=CC=C1

Synonyms:

• 2-Iodo Methyl Benzoate
• 2-Iodobenzoic Acid Methyl Ester
• Benzoic acid, 2-iodo-, methyl ester
• Benzoic acid, o-iodo-, methyl ester
• Methyl o-iodobenzoate
• NSC 34638
• Methyl 2-iodobenzoate

Methyl 2-Iodobenzoate

CAS: 610-97-9

Formula: C₈H₇IO₂

Purity: >98.0%(GC)

Color and Shape: Light orange to Yellow to Green clear liquid

Molecular weight: 262.05

Ref: 3B-I0586

Methyl 2-iodobenzoate

CAS: 610-97-9

Formula: C₈H₇IO₂

Purity: 99.0%

Color and Shape: Clear

Molecular weight: 262.046

Ref: 10-F005544

Methyl 2-iodobenzoate, 98%

CAS: 610-97-9

2-Iodobenzoic Acid, methyl ester; 2-Iodobenzoic Acid is a starting material for the preparation of iodosobenzoate, selectivity and environment management. Trivalent iodine compounds perform mild oxidations, oxidative couplings, special iodinations and acetoxylations. Iodobenzoates are used as anti-i

Formula: C₈H₇IO₂

Purity: 98%

Color and Shape: Liquid, Clear colorless to yellow

Molecular weight: 262.05

Ref: 02-A13204

2-Iodobenzoic Acid Methyl Ester

CAS: 610-97-9

Formula: C₈H₇IO₂

Purity: 98%

Color and Shape: Liquid

Molecular weight: 262.0445

Ref: IN-DA0033D5

Methyl 2-iodobenzoate, min. 98%

CAS: 610-97-9

Formula: C₈H₇IO₂

Purity: min. 98%

Color and Shape: Clear, colorless to yellow liquid

Molecular weight: 262.05

Ref: 08-06-0076

Methyl 2-iodobenzoate

CAS: 610-97-9

Methyl 2-iodobenzoate

Formula: C₈H₇IO₂

Purity: 98%

Color and Shape: pale yellow liquid

Molecular weight: 262.04g/mol

Ref: 54-OR23611

Methyl 2-Iodobenzoate

Controlled Product

CAS: 610-97-9

Stability Light Sensitive
Applications Methyl 2-Iodobenzoate is used as a reagent in the synthesis of Montelukast Sodium Salt (M568000); a selective leukotriene D4-receptor antagonist that is used as an antiasthmatic. Methyl 2-Iodobenzoate is also used as a reagent in the synthesis of isoquinolinone-based tricycles as polyribose polymerase-1 inhibitors.
References Bollikonda, S., et al.: J. Org. Chem., 80, 3891 (2015); Labelle, M., et al.: Bioorg. Med. Chem. Lett., 5, 283 (1995); Jones, T.R., et al.: Can. J. Physiol. Pharmacol., 73, 191 (1995); Markham, A. and Faulds, D.: Drugs, 56, 251 (1998); Chen, J., et al.: Bioorg. Med. Chem. Lett., 24, 2669 (2014)

Formula: C₈H₇IO₂

Color and Shape: Colourless To Light Yellow

Molecular weight: 262.04

Ref: TR-M313675

2-Iodobenzoic acid methyl ester

CAS: 610-97-9

2-Iodobenzoic acid methyl ester is a palladium complex that can be used as a catalyst for the hydrolysis of ketoesters, imines, and halides. The reaction mechanism involves the coordination of the metal center to the carboxylate or amine group on the substrate, followed by a nucleophilic attack at the benzoate or chloride group. The resulting product is an alkyl halide. 2-Iodobenzoic acid methyl ester has been shown to catalyze the cross-coupling of diphenyl ethers with various amines in water and in organic solvents.

Formula: C₈H₇IO₂

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 262.04 g/mol

Ref: 3D-FI02156