CAS 61043-53-6

N-(3-carboxypropanoyl)-L-alanyl-N-{(2S)-2-[(4-nitrophenyl)amino]-3-phenylpropanoyl}-L-alaninamide

Description:

N-(3-carboxypropanoyl)-L-alanyl-N-{(2S)-2-[(4-nitrophenyl)amino]-3-phenylpropanoyl}-L-alaninamide, with CAS number 61043-53-6, is a complex organic compound characterized by its peptide-like structure, which includes amino acid components and functional groups that contribute to its biochemical properties. This substance features multiple functional groups, including carboxylic acids and amides, which can influence its solubility, reactivity, and interaction with biological systems. The presence of a nitrophenyl group suggests potential applications in biochemical assays or as a probe in molecular biology due to its ability to participate in electronic interactions. Additionally, the compound's chirality, indicated by the presence of L-alanine residues, may affect its biological activity and specificity in interactions with enzymes or receptors. Overall, this compound's unique structure and functional characteristics make it of interest in fields such as medicinal chemistry, biochemistry, and drug design, where understanding its properties can lead to insights into its potential applications.

Formula: C₂₅H₂₉N₅O₈

InChI: InChI=1/C25H29N5O8/c1-15(26-21(31)12-13-22(32)33)23(34)27-16(2)24(35)29-25(36)20(14-17-6-4-3-5-7-17)28-18-8-10-19(11-9-18)30(37)38/h3-11,15-16,20,28H,12-14H2,1-2H3,(H,26,31)(H,27,34)(H,32,33)(H,29,35,36)/t15-,16-,20-/m0/s1

SMILES: C[C@@H](C(=N[C@@H](C)C(=NC(=O)[C@H](Cc1ccccc1)Nc1ccc(cc1)N(=O)=O)O)O)N=C(CCC(=O)O)O

Synonyms:

• L-Phenylalaninamide, N-(3-carboxy-1-oxopropyl)-L-alanyl-L-alanyl-N-(4-nitrophenyl)-
• succinyl-alanyl-alanyl-phenylalanine-4-nitroanilide
• Suc-AAF-pNA
• 4-[[(2S)-1-[[(2S)-1-[[(2S)-2-(4-nitroanilino)-3-phenylpropanoyl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
• Suc-Ala-Ala-Phe-pNA (L-1580.0250)

Suc-Ala-Ala-Phe-pNA

CAS: 61043-53-6

Suc-Ala-Ala-Phe-pNA is a peptide that is being studied for its potential to act as an anticancer agent. It inhibits the growth of tumor cells by binding to the neurokinin receptor and thereby blocking the production of substances such as epidermal growth factor, which promote tumor growth. Suc-Ala-Ala-Phe-pNA also has been shown to inhibit the activity of enzymes involved in glucocorticoid receptors, which are proteins that play a key role in regulating the immune response. This peptide also has been shown to be active against mouse skin cells and human prostate cancer cells. In addition, it is believed that this peptide may be useful in gene therapy because it can induce apoptosis in tumor cells without affecting normal tissue.

Formula: C₂₅H₂₉N₅O₈

Purity: Min. 95%

Molecular weight: 527.53 g/mol

Ref: 3D-FS110759