CAS 61043-65-0

4-[[(1S)-1-Methyl-2-[(4-nitrophenyl)amino]-2-oxoethyl]amino]-4-oxobutanoic acid

Description:

4-[[(1S)-1-Methyl-2-[(4-nitrophenyl)amino]-2-oxoethyl]amino]-4-oxobutanoic acid, with the CAS number 61043-65-0, is a complex organic compound characterized by its multi-functional groups. It features an amino acid structure, which includes a carboxylic acid group, contributing to its acidic properties. The presence of a nitrophenyl group indicates potential for electrophilic reactivity, while the methyl and oxo groups suggest it may participate in various chemical reactions, including nucleophilic substitutions and condensation reactions. This compound is likely to exhibit polar characteristics due to the presence of both amino and carboxylic acid functionalities, which can influence its solubility in polar solvents. Additionally, the stereochemistry indicated by the (1S) configuration suggests specific spatial arrangements that may affect its biological activity and interactions with other molecules. Overall, this compound's unique structure may render it of interest in pharmaceutical research or as a potential intermediate in organic synthesis.

Formula: C₁₃H₁₅N₃O₆

InChI: InChI=1S/C13H15N3O6/c1-8(14-11(17)6-7-12(18)19)13(20)15-9-2-4-10(5-3-9)16(21)22/h2-5,8H,6-7H2,1H3,(H,14,17)(H,15,20)(H,18,19)/t8-/m0/s1

InChI key: InChIKey=WIFDUCQVCBVJOF-QMMMGPOBSA-N

SMILES: N(C([C@@H](NC(CCC(O)=O)=O)C)=O)C1=CC=C(N(=O)=O)C=C1

Synonyms:

• 3-Carboxypropionyl-L-alanine-p-nitroanilide
• Butanoic acid, 4-[[(1S)-1-methyl-2-[(4-nitrophenyl)amino]-2-oxoethyl]amino]-4-oxo-
• 4-[[(1S)-1-Methyl-2-[(4-nitrophenyl)amino]-2-oxoethyl]amino]-4-oxobutanoic acid
• Butanoic acid, 4-[[1-methyl-2-[(4-nitrophenyl)amino]-2-oxoethyl]amino]-4-oxo-, (S)-

Suc-Ala-pNA

CAS: 61043-65-0

Suc-Ala-pNA is a molecule that is composed of alendronic acid, which is a prodrug that has been conjugated to polyethylene glycol and polyaspartic acid. The pNA moiety in the molecule is capable of penetrating the mucosal membrane and can be cleaved by aminopeptidase and peptidase to release active alendronic acid. The mucoadhesive polymers increase the permeability of the molecule, while the spacer group increases its stability. Suc-Ala-pNA has been shown to have a high affinity for bone mineralization, as it reacts with bone mineral surfaces to form a covalent bond. This reaction mechanism leads to increased bone mineralization, which may help treat osteoporosis.

Formula: C₁₃H₁₅N₃O₆

Purity: Min. 95%

Molecular weight: 309.27 g/mol

Ref: 3D-SAN-3116