CAS 61071-29-2

3(2H)-Pyridazinone, 5-amino-4-chloro-, hydrazone

Description:

3(2H)-Pyridazinone, 5-amino-4-chloro-, hydrazone, identified by CAS number 61071-29-2, is a chemical compound characterized by its pyridazinone core structure, which features a hydrazone functional group. This compound typically exhibits properties associated with both pyridazine and hydrazone functionalities, including potential biological activity. The presence of the amino and chloro substituents can influence its reactivity and solubility in various solvents. Pyridazinones are known for their diverse applications in medicinal chemistry, often serving as intermediates in the synthesis of pharmaceuticals. The hydrazone linkage may contribute to the compound's stability and reactivity, making it a candidate for further chemical modifications. Additionally, the chlorine atom can enhance the compound's lipophilicity, potentially affecting its pharmacokinetic properties. Overall, this compound's unique structural features suggest it may possess interesting biological activities, warranting further investigation in the context of drug development and other chemical applications.

Formula: C₄H₆ClN₅

5-Chloro-6-hydrazinylpyridazin-4-amine

CAS: 61071-29-2

5-Chloro-6-hydrazinylpyridazin-4-amine (5CHP) is a nucleophilic anticancer agent that is synthesized by the ammonolysis of 5,6-dichloropyridazine. 5CHP inhibits cell proliferation and induces apoptosis in vitro and in vivo. 5CHP has been shown to inhibit the growth of L1210 cells, which are mouse leukemia cells, and primary rat glioma cells. This drug also inhibits the proliferation of human breast cancer cells with high levels of p53 mutations. 5CHP has potent anticancer activity against various types of cancer cells and is a potential alternative to other anticancer drugs such as doxorubicin, cisplatin, or paclitaxel.

Formula: C₄H₆ClN₅

Purity: Min. 95%

Molecular weight: 159.58 g/mol

Ref: 3D-LCA07129