CymitQuimica logo

CAS 6112-76-1

:

6-Mercaptopurine monohydrate

Description:
6-Mercaptopurine monohydrate is a purine analog and an antimetabolite used primarily in the treatment of certain types of leukemia and autoimmune diseases. It is characterized by its chemical formula C5H6N4S·H2O, indicating the presence of a mercapto group (-SH) that contributes to its reactivity and biological activity. The substance appears as a white to off-white crystalline powder and is soluble in water, which facilitates its administration in clinical settings. Its mechanism of action involves the inhibition of purine nucleotide synthesis, thereby interfering with DNA and RNA synthesis, which is crucial for rapidly dividing cells. 6-Mercaptopurine is often administered in conjunction with other medications to enhance therapeutic efficacy and reduce the risk of resistance. Due to its potential for toxicity, careful monitoring of blood counts and liver function is essential during treatment. Additionally, it is important to consider genetic factors, such as variations in the TPMT enzyme, which can affect individual responses to the drug.
Formula:C5H4N4S·H2O
InChI:InChI=1S/C5H4N4S.H2O/c10-5-3-4(7-1-6-3)8-2-9-5;/h1-2H,(H2,6,7,8,9,10);1H2
InChI key:InChIKey=WFFQYWAAEWLHJC-UHFFFAOYSA-N
SMILES:S=C1C2=C(NC=N1)N=CN2.O
Synonyms:
  • 1,4,5,7-Tetrahydro-6H-Purine-6-Thione Hydrate
  • 1,7-Dihydro-6H-Purin-6-Thion,Monohydrat
  • 1,7-Dihydro-6H-Purine-6-Thionemonohydrate
  • 1,7-Dihydro-6H-Purine-6-Thionmonohydrate
  • 3,7-Dihydro-6H-Purine-6-Thione Hydrate
  • 6-Mercapto Purine
  • 6-Mercaptopurine Hydrate
  • 6-Merkaptopurin,Monohydrat
  • 6-Purinethiol Monohydrate
  • 6-Thiohypoxanthine Monohydrate
  • See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
products per page.Found 22 products.