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CAS 612069-26-8

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Azithromycin F

Description:
Azithromycin F, identified by the CAS number 612069-26-8, is a semi-synthetic macrolide antibiotic derived from erythromycin. It exhibits broad-spectrum antibacterial activity, primarily targeting Gram-positive bacteria and some Gram-negative organisms. The compound functions by inhibiting bacterial protein synthesis through binding to the 50S ribosomal subunit, effectively disrupting the translation process. Azithromycin F is known for its favorable pharmacokinetic properties, including good oral bioavailability and a long half-life, which allows for once-daily dosing and shorter treatment courses compared to other antibiotics. It is commonly used to treat various infections, including respiratory tract infections, skin infections, and sexually transmitted diseases. Additionally, Azithromycin F has anti-inflammatory properties and is sometimes utilized in the management of certain chronic inflammatory conditions. Its safety profile is generally favorable, although potential side effects may include gastrointestinal disturbances and, in rare cases, cardiac arrhythmias. Overall, Azithromycin F is a valuable therapeutic agent in modern medicine, particularly in the treatment of bacterial infections.
Formula:C38H72N2O13
InChI:InChI=1S/C38H72N2O13/c1-14-27-38(9,47)31(43)23(5)40(12)18-20(2)16-36(7,46)33(53-35-29(42)26(39(10)11)15-21(3)49-35)22(4)30(25(19-41)34(45)51-27)52-28-17-37(8,48-13)32(44)24(6)50-28/h20-33,35,41-44,46-47H,14-19H2,1-13H3/t20-,21-,22+,23-,24+,25-,26+,27-,28+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1
InChI key:InChIKey=FOKFKPIVUOKMAB-KRYDKTARSA-N
SMILES:O([C@@H]1[C@@H](CO)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)N(C)C[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@H](O)[C@@H](N(C)C)C[C@@H](C)O2)[C@H]1C)[C@H]3C[C@](OC)(C)[C@@H](O)[C@H](C)O3
Synonyms:
  • 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-14-(hydroxymethyl)-3,5,6,8,10,12-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-
  • (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-14-(hydroxymethyl)-3,5,6,8,10,12-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one
  • Azithromycin F
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