CAS 612069-31-5

(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-[methyl[(4-methylphenyl)sulfonyl]amino]-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one

Description:

The chemical substance with the name provided is a complex organic molecule characterized by its intricate stereochemistry and multiple functional groups. It features a polycyclic structure with several hydroxyl groups, indicating potential for hydrogen bonding and solubility in polar solvents. The presence of dideoxy sugars suggests it may have biological activity, possibly interacting with specific enzymes or receptors. The molecule also contains a sulfonamide group, which can enhance its pharmacological properties. Its multiple methyl groups contribute to hydrophobic characteristics, influencing its overall solubility and membrane permeability. The specific stereochemistry, denoted by the R and S configurations, is crucial for its biological activity, as even slight changes can significantly alter its interaction with biological targets. This compound may be of interest in medicinal chemistry, particularly in the development of therapeutics, due to its structural complexity and potential bioactivity. Overall, its unique combination of features makes it a subject of interest for further research in various chemical and biological applications.

Formula: C₄₄H₇₆N₂O₁₄S

InChI: InChI=1S/C44H76N2O14S/c1-15-33-44(11,52)37(48)29(7)45(12)23-25(3)21-42(9,51)39(27(5)36(28(6)40(50)58-33)59-34-22-43(10,55-14)38(49)30(8)57-34)60-41-35(47)32(20-26(4)56-41)46(13)61(53,54)31-18-16-24(2)17-19-31/h16-19,25-30,32-39,41,47-49,51-52H,15,20-23H2,1-14H3/t25-,26-,27+,28-,29-,30+,32+,33-,34+,35-,36+,37-,38+,39-,41+,42-,43-,44-/m1/s1

InChI key: InChIKey=PAZSFKCLSYSRGC-XOZZEHTCSA-N

SMILES: O([C@@H]1[C@@H](C)[C@H](O[C@H]2C[C@](OC)(C)[C@@H](O)[C@H](C)O2)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)N(C)C[C@H](C)C[C@@]1(C)O)[C@H]3[C@H](O)[C@@H](N(S(=O)(=O)C4=CC=C(C)C=C4)C)C[C@@H](C)O3

Synonyms:

• (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-[methyl[(4-methylphenyl)sulfonyl]amino]-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one
• 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-[methyl[(4-methylphenyl)sulfonyl]amino]-β-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-

3'-Demethyl-3'-N-[(4-methylphenyl)sulfonyl]azithromycin

CAS: 612069-31-5

Sulfonamides, nesoi

Formula: C₄₄H₇₆N₂O₁₄S

Color and Shape: White Off-White Solid

Molecular weight: 888.50173

Ref: 45-1A00840

Azithromycin EP Impurity G

CAS: 612069-31-5

Formula: C₄₄H₇₆N₂O₁₄S

Color and Shape: White To Off-White Solid

Molecular weight: 889.15

Ref: 4Z-A-2613

Azithromycin EP Impurity G

CAS: 612069-31-5

Formula: C₄₄H₇₆N₂O₁₄S

Molecular weight: 889.14

Ref: ST-EA-CP-A37007

3’-N-Desmethyl-3’-N-tosyl Azithromycin

CAS: 612069-31-5

Impurity Azithromycin EP Impurity G
Applications 3’-N-Desmethyl-3’-N-tosyl Azithromycin (Azithromycin EP Impurity G) is an Azithromycin (A927000) impurity.
References Kirst, H., et al.: Antimicrob. Agents Chemother., 33, 1419 (1989), Gandhi, R., et al.: J. Pharm. Biomed. Anal., 23, 1073 (2000),

Formula: C₄₄H₇₆N₂O₁₄S

Color and Shape: White To Off-White

Molecular weight: 889.14

Ref: TR-D291700

3'-N-Desmethyl-3'-N-tosyl azithromycin

CAS: 612069-31-5

3'-N-Desmethyl-3'-N-tosyl azithromycin is a semi-synthetic macrolide antibiotic analog, which is a derivative of azithromycin, a well-known member of the macrolide class of antibiotics. This compound is synthesized through chemical modifications of the parent molecule, azithromycin, to potentially enhance its pharmacokinetic and pharmacodynamic properties.

Formula: C₄₄H₇₆N₂O₁₄S

Purity: Min. 95%

Molecular weight: 889.15 g/mol

Ref: 3D-AD21350