CAS 61270-58-4

Cefonicid

Description:

Cefonicid is a semisynthetic cephalosporin antibiotic that belongs to the beta-lactam class of antibiotics. It is primarily used to treat a variety of bacterial infections, particularly those caused by Gram-negative and some Gram-positive bacteria. Cefonicid exhibits a broad spectrum of activity and is effective against organisms such as Escherichia coli and Klebsiella pneumoniae. The compound is characterized by its stability against certain beta-lactamases, which enhances its efficacy in treating resistant infections. Cefonicid is typically administered via injection and is known for its relatively long half-life, allowing for less frequent dosing compared to some other antibiotics. Its pharmacokinetics involve distribution throughout body tissues and fluids, with renal excretion being the primary route of elimination. As with other antibiotics, potential side effects may include allergic reactions, gastrointestinal disturbances, and alterations in normal flora. Overall, Cefonicid represents an important option in the arsenal of antibiotics for managing bacterial infections, particularly in a clinical setting.

Formula: C₁₈H₁₈N₆O₈S₃

InChI: InChI=1S/C18H18N6O8S3/c25-13(9-4-2-1-3-5-9)14(26)19-11-15(27)24-12(17(28)29)10(6-33-16(11)24)7-34-18-20-21-22-23(18)8-35(30,31)32/h1-5,11,13,16,25H,6-8H2,(H,19,26)(H,28,29)(H,30,31,32)/t11-,13-,16-/m1/s1

InChI key: InChIKey=DYAIAHUQIPBDIP-AXAPSJFSSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](NC([C@H](O)C3=CC=CC=C3)=O)C2=O)(SCC1CSC=4N(CS(=O)(=O)O)N=NN4)[H]

Synonyms:

• (6R,7R)-7-[[(2R)-2-Hydroxy-2-phenylacetyl]amino]-8-oxo-3-[[[1-(sulfomethyl)-1H-tetrazol-5-yl]thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7R)-7-{[(2R)-2-hydroxy-2-phenylacetyl]amino}-8-oxo-3-({[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl}methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7R)-7-{[hydroxy(phenyl)acetyl]amino}-8-oxo-3-({[1-(sulfomethyl)-1H-tetrazol-5-yl]sulfanyl}methyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[(hydroxyphenylacetyl)amino]-8-oxo-3-[[[1-(sulfomethyl)-1H-tetrazol-5-yl]thio]methyl]-, [6R-[6α,7β(R*)]]-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-2-hydroxy-2-phenylacetyl]amino]-8-oxo-3-[[[1-(sulfomethyl)-1H-tetrazol-5-yl]thio]methyl]-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-hydroxyphenylacetyl]amino]-8-oxo-3-[[[1-(sulfomethyl)-1H-tetrazol-5-yl]thio]methyl]-, (6R,7R)-
• Monicid
• Cefonicid

Cefonicid

CAS: 61270-58-4

Formula: C₁₈H₁₈N₆O₈S₃

Molecular weight: 542.57

Ref: 7W-GA5722

Cefonicid

CAS: 61270-58-4

Formula: C₁₈H₁₈N₆O₈S₃

Molecular weight: 542.57

Ref: 4Z-C-189001

Cefonicid

CAS: 61270-58-4

Cefonicid is a semisynthetic cephalosporin antibiotic, which is derived from the naturally occurring compound cephalosporin C, obtained from the mold *Cephalosporium acremonium*. Its mode of action involves inhibiting bacterial cell wall synthesis by binding to penicillin-binding proteins, leading to cell lysis and death, thereby exhibiting bactericidal activity.

Formula: C₁₈H₁₆N₆O₈S₃

Purity: Min. 95%

Molecular weight: 540.55 g/mol

Ref: 3D-FC45804

Cefonicid (free base)

CAS: 61270-58-4

Cefonicid: second-gen cephalosporin, IV/IM, treats UTIs, respiratory, bone, and soft tissue infections by blocking cell wall formation.

Formula: C₁₈H₁₈N₆O₈S₃

Color and Shape: Solid

Molecular weight: 542.57

Ref: TM-T68999