CAS 61272-76-2

4-Fluoro-2-iodoaniline

Description:

4-Fluoro-2-iodoaniline is an organic compound characterized by the presence of both fluorine and iodine substituents on an aniline structure. It features a fluorine atom at the para position and an iodine atom at the ortho position relative to the amino group on the benzene ring. This compound is typically a solid at room temperature and is known for its potential applications in pharmaceuticals and organic synthesis due to the reactivity of the halogen substituents. The presence of the fluorine atom can enhance the lipophilicity and metabolic stability of the compound, while the iodine atom can facilitate various coupling reactions in synthetic chemistry. Additionally, 4-Fluoro-2-iodoaniline may exhibit unique electronic properties due to the differing electronegativities of the halogens, influencing its behavior in chemical reactions. Safety considerations should be taken into account when handling this compound, as both fluorine and iodine can pose health risks. Proper storage and handling protocols are essential to ensure safety in laboratory environments.

Formula: C₆H₅FIN

InChI: InChI=1/C6H5FIN/c7-4-1-2-6(9)5(8)3-4/h1-3H,9H2

InChI key: InChIKey=SETOTRGVPANENO-UHFFFAOYSA-N

SMILES: c1cc(c(cc1F)I)N

Synonyms:

• 2-Iodo-4-fluoroaniline
• 4-Fluoro-2-Indoaniline
• 4-Fluoro-2-iodobenzenamine
• 4-Fluoro-2-iodophenylamine
• Benzenamine, 4-fluoro-2-iodo-

4-Fluoro-2-iodoaniline, 96%

CAS: 61272-76-2

4-Fluoro-2-iodoaniline is used as an organic chemical synthesis intermediate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or

Formula: C₆H₅FIN

Purity: 96%

Color and Shape: Liquid, Clear to opaque pale brown to brown to purple to black

Molecular weight: 237.02

Ref: 02-B25499

4-Fluoro-2-iodoaniline

CAS: 61272-76-2

Formula: C₆H₅FIN

Purity: 96%

Color and Shape: Liquid, Clear

Molecular weight: 237.016

Ref: 10-F019309

4-Fluoro-2-iodoaniline

CAS: 61272-76-2

Formula: C₆H₅FIN

Purity: 98%

Color and Shape: Solid

Molecular weight: 237.0135

Ref: IN-DA003LD3

4-Fluoro-2-iodoaniline

CAS: 61272-76-2

4-Fluoro-2-iodoaniline

Formula: C₆H₅FIN

Purity: 98%

Color and Shape: very dark brown/black/purple fused solid

Molecular weight: 237.01g/mol

Ref: 54-PC3452

4-Fluoro-2-iodoaniline

CAS: 61272-76-2

Formula: C₆H₅FIN

Purity: >98.0%(GC)(T)

Color and Shape: Colorless to Brown clear liquid

Molecular weight: 237.02

Ref: 3B-F0706

4-Fluoro-2-iodoaniline

Controlled Product

CAS: 61272-76-2

Applications 4-Fluoro-2-iodoaniline is a useful reactant for the synthesis of cyclohepta[b]indole scaffold via annulative two-carbon ring-expansion.
References Tymann, D. C., et al.: Chem. Eur. J, 26, 11974 (2020)

Formula: C₆H₅FIN

Color and Shape: Neat

Molecular weight: 237.01

Ref: TR-F592020