CAS 61281-37-6

Schisandrin B

Description:

Schisandrin B is a bioactive lignan compound primarily derived from the fruit of Schisandra chinensis, a plant known for its medicinal properties in traditional Chinese medicine. It is characterized by its molecular formula, which typically includes carbon, hydrogen, and oxygen atoms, reflecting its organic nature. Schisandrin B exhibits a range of pharmacological activities, including antioxidant, anti-inflammatory, and hepatoprotective effects, making it of interest in both research and therapeutic applications. The compound is often studied for its potential benefits in enhancing liver function and protecting against oxidative stress. Additionally, Schisandrin B has been investigated for its neuroprotective properties and its role in modulating various signaling pathways. Its solubility and stability can vary depending on the solvent and environmental conditions, which is important for its application in formulations. Overall, Schisandrin B represents a significant area of interest in natural product chemistry and pharmacology, with ongoing research aimed at elucidating its mechanisms of action and potential health benefits.

Formula: C₂₃H₂₈O₆

InChI: InChI=1/C23H28O6/c1-12-7-14-9-16(24-3)20(25-4)22(26-5)18(14)19-15(8-13(12)2)10-17-21(23(19)27-6)29-11-28-17/h9-10,12-13H,7-8,11H2,1-6H3/t12-,13+/m0/s1

InChI key: InChIKey=RTZKSTLPRTWFEV-UHFFFAOYSA-N

SMILES: O(C)C1=C2C=3C(=CC(OC)=C(OC)C3OC)CC(C)C(C)CC2=CC4=C1OCO4

Synonyms:

• (6R,7S)-1,2,3,13-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxole
• (6S,7R)-1,2,3,13-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxole
• (±)-γ-Schisandrin
• (±)-γ-Schizandrin
• 1,2,3,13-Tetramethoxy-6,7-Dimethyl-5,6,7,8-Tetrahydrobenzo[3',4']Cycloocta[1',2':4,5]Benzo[1,2-D][1,3]Dioxole
• Benzo(3,4)cycloocta(1,2-f)(1,3)benzodioxole, 5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, stereoisomer
• Benzo[3,4]cycloocta[1,2-f][1,3]benzodioxole, 5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, (6R,7S,13aR)-rel-
• Schisandrin B
• Wuweizisu B
• gamma-Schisandrin
• gamma-Schizandrin
• rel-(6R,7S,13aR)-5,6,7,8-Tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethylbenzo[3,4]cycloocta[1,2-f][1,3]benzodioxole
• S(-) WUWEI ZI SU
• 6,7-dimethyl-, stereoisomer
• 5,6,7,8-Tetrahydro-1,2,3,13-tetramethoxy-
• 7-dimethyl-ethoxy-stereoisomer
• benzo(3,4)cycloocta(1,2-f)(1,3)benzodioxole,5,6,7,8-tetrahydro-1,2,3,13-tetram
• S(-) SCHISANDRIN B
• GEMA-SCHIZANDRIN
• Benzo [3,4] cycloocta [1,2-f][1,3]benzodioxole
• WUWEIZISU B 98.0% BY HPLC
• SCHIZANDRIN B
• S(-) SCHIZANDRIN B
• GOMISIN N
• S(-)-SCHISANDRIN
• SCHISANDRIN(SCHISANDROL A)(P)

Benzo[3,4]cycloocta[1,2-f][1,3]benzodioxole,5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, stereoisomer

CAS: 61281-37-6

Formula: C₂₃H₂₈O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 400.4648

Ref: IN-DA00IKJR

Schisandrin B

CAS: 61281-37-6

Schisandrin B

Purity: ≥98%

Molecular weight: 400.46g/mol

Ref: 54-BUP12457

Schisandrin B

CAS: 61281-37-6

Formula: C₂₃H₂₈O₆

Purity: (HPLC) ≥ 98.0%

Color and Shape: White to beige powder

Molecular weight: 400.46

Ref: 7W-GP9899

Schisandrin B

CAS: 61281-37-6

Schisandrin B, a kind of ATR and P-gp inhibitor with high safety, has been shown to produce antioxidant effect on rodent liver and heart. It also has anti-photoaging, and presents promising activities for future development of protective agents against CisPt nephrotoxicity. Combination of schizandrin B and paclitaxel(PTX) can enhance anti-tumor effects and relieve side effects of PTX on rats with mammary carcinoma.

Formula: C₂₃H₂₈O₆

Purity: 95%~99%

Molecular weight: 400.471

Ref: BP-BP1262

Schisandrin B

CAS: 61281-37-6

Schisandrin B (Schisandrin B (Sch B)) has an antioxidant effect on rodent liver and heart.

Formula: C₂₃H₂₈O₆

Purity: 99.02% - >99.99%

Color and Shape: Solid

Molecular weight: 400.46

Ref: TM-T2925

Schizandrin b

CAS: 61281-37-6

Ether phenol

Formula: C₂₃H₂₈O₆

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 400.47

Ref: 5G-89786

Schizandrin B

Controlled Product

CAS: 61281-37-6

Schizandrin B is a natural compound that is found in the seeds of Schisandra chinensis. It has been shown to have an anti-inflammatory effect and protect against oxidative injury. Schizandrin B has been shown to inhibit the expression of toll-like receptor 4 (TLR4) in 3T3-L1 preadipocytes, which may be due to its ability to induce nuclear DNA fragmentation. This compound also has a matrix effect on cells by increasing cell stiffness and preventing apoptosis. The low-dose group had significantly less oxidative injury than the high-dose group, which was likely due to its ability to inhibit p-glycoprotein (Pgp).

Formula: C₂₃H₂₈O₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 400.46 g/mol

Ref: 3D-FS31355