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CAS 61318-90-9

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Sulconazole

Description:
Sulconazole is an antifungal agent primarily used in the treatment of dermatological infections caused by fungi. It belongs to the class of imidazole derivatives and exhibits broad-spectrum antifungal activity. The compound works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby disrupting their integrity and function. Sulconazole is typically formulated as a topical cream or solution, allowing for localized treatment of conditions such as athlete's foot, ringworm, and other superficial fungal infections. Its efficacy is complemented by a favorable safety profile, with minimal systemic absorption when applied topically. The chemical structure of sulconazole includes a sulfonamide group, which contributes to its pharmacological properties. As with many antifungal agents, resistance can develop, making appropriate use and adherence to treatment guidelines essential for optimal outcomes. Overall, sulconazole is a valuable option in the antifungal arsenal, particularly for dermatological applications.
Formula:C18H15Cl3N2S
InChI:InChI=1/C18H15Cl3N2S.HNO3/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21;2-1(3)4/h1-9,12,18H,10-11H2;(H,2,3,4)
InChI key:InChIKey=AFNXATANNDIXLG-UHFFFAOYSA-N
SMILES:C(CN1C=CN=C1)(SCC2=CC=C(Cl)C=C2)C3=C(Cl)C=C(Cl)C=C3
Synonyms:
  • (±)-1-[2,4-Dichloro-b-[(p-chlorobenzyl)thio]phenethyl]imidazole
  • 1-(2-((4-Chlorobenzyl)thio)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole
  • 1-[2-[(4-Chlorophenyl)methylsulfanyl]-2-(2,4-dichlorophenyl)ethyl]imidazole
  • 1-[2-[[(4-Chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
  • 1-{2-[(4-Chlorobenzyl)sulfanyl]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
  • 1-{2-[(4-chlorobenzyl)sulfanyl]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole nitrate (1:1)
  • 1H-imidazole, 1-[2-[[(4-chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-
  • 61318-90-9
  • (±)-Sulconazole
  • Sulconazole
  • See more synonyms
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