CAS 61319-46-8
:Pregna-1,4-diene-3,20-dione, 21-chloro-9-fluoro-11,17-dihydroxy-16-methyl-, (11β,16α)- (9CI)
Description:
Pregna-1,4-diene-3,20-dione, 21-chloro-9-fluoro-11,17-dihydroxy-16-methyl-, (11β,16α)-, commonly known as a synthetic corticosteroid, is characterized by its complex steroid structure, which includes a fluorine atom and a chlorine atom, contributing to its biological activity. This compound features a pregnane backbone, which is typical of steroid hormones, and exhibits a range of pharmacological properties, primarily anti-inflammatory and immunosuppressive effects. The presence of hydroxyl groups at specific positions enhances its solubility and receptor binding affinity, while the diene and keto functionalities are crucial for its hormonal activity. This substance is often utilized in therapeutic applications, particularly in the treatment of various inflammatory and autoimmune conditions. Its specific stereochemistry, indicated by the (11β,16α) configuration, plays a significant role in determining its interaction with steroid receptors and overall efficacy. As with many corticosteroids, careful consideration of dosage and potential side effects is essential in clinical use.
Formula:C22H28ClFO4
Synonyms:- Pregna-1,4-diene-3,20-dione, 21-chloro-9-fluoro-11,17-dihydroxy-16-methyl-, (11β,16α)- (9CI)
- 16-Epi-Clobetasol
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