CAS 613263-00-6

6-(2-Aminophenoxy)-1,2-benzisothiazol-3-aminedihydrochloride

CAS: 613263-00-6

Formula: C₁₃H₁₃Cl₂N₃OS

Purity: 98%

Molecular weight: 330.2328

Ref: IN-DA01ENJ9

M62812

CAS: 613263-00-6

M62812

Purity: ≥95%

Molecular weight: 330.23g/mol

Ref: 54-BUP10614

6-(2-aminophenoxy)-1,2-benzothiazol-3-amine dihydrochloride

CAS: 613263-00-6

Purity: 95.0%

Molecular weight: 330.2300109863281

Ref: 10-F541827

M62812

CAS: 613263-00-6

M62812 is a potent, specific and selective inhibitor of the mitochondrial enzyme, ATP synthase. It has been shown to modulate the expression of proteins involved in apoptotic cell death, such as Bax and cytochrome C. M62812 also inhibits mitochondrial biogenesis and cellular ATP production, resulting in necrotic cell death. This agent has also been shown to have immunomodulatory effects on microglia cells in vitro by inhibiting Toll-like receptor 4 (TLR4). In addition, M62812 has been found to be effective in animal models of autoimmune diseases.

Formula: C₁₃H₁₃Cl₂N₃OS

Purity: Min. 95%

Molecular weight: 330.2 g/mol

Ref: 3D-NZA26300

M62812

CAS: 613263-00-6

TLR4 inhibitor blocks LPS-induced NF-κB (IC50=2.4μg/mL), cytokines in PBMCs/HUVECs, and extends life in septic shock mice.

Formula: C₁₃H₁₃Cl₂N₃OS

Purity: 99.07%

Color and Shape: Solid

Molecular weight: 330.23

Ref: TM-T37292