CAS 61364-37-2

(-)-Mirtazapine

Description:

(-)-Mirtazapine is an antidepressant medication primarily used to treat major depressive disorder. It belongs to the class of drugs known as noradrenergic and specific serotonergic antidepressants (NaSSAs). The compound exhibits a unique mechanism of action by antagonizing certain serotonin receptors (5-HT2 and 5-HT3) while enhancing norepinephrine and serotonin release through its action on adrenergic receptors. This dual action contributes to its efficacy in alleviating depressive symptoms. Chemically, (-)-Mirtazapine is characterized by its tetracyclic structure, which includes a central piperazino group. It is typically administered in oral form and is known for its sedative properties, making it beneficial for patients with insomnia associated with depression. Common side effects may include sedation, weight gain, and increased appetite. The substance is classified under the category of prescription medications and should be used under medical supervision due to potential interactions with other drugs and individual health conditions.

Formula: C₁₇H₁₉N₃

InChI: InChI=1/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3/t16-/m0/s1

InChI key: InChIKey=RONZAEMNMFQXRA-INIZCTEOSA-N

SMILES: CN1C[C@@]2(N(C=3C(CC=4C2=CC=CC4)=CC=CN3)CC1)[H]

Synonyms:

• (-)-Mirtazapine
• (14bR)-1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine
• (7R)-5-Methyl-2,5,19-triazatetracyclo[13.4.0.0[2,7].0[8,13]]nonadeca-1(19),8,10,12,15,17-hexaene
• (R)-1,2,3,4,10,14b-Hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)(2)benzazepine
• (R)-2-Methyl-1,2,3,4,10,14b-hexahydrobenzo[c]pyrazino[1,2-a]pyrido[3,2-f]azepine
• (R)-6-Azamianserin
• (R)-Mirtazapine
• (R)-Org 3770
• 262-735-5
• Org 44-19
• Pyrazino[2,1-a]pyrido[2,3-c][2]benzazepine, 1,2,3,4,10,14b-hexahydro-2-methyl-, (14bR)-
• Pyrazino[2,1-a]pyrido[2,3-c][2]benzazepine, 1,2,3,4,10,14b-hexahydro-2-methyl-, (R)-
• (R)-Mirtazapine-13C-d3
• (R)-Org3770

(R)-Mirtazapine

CAS: 61364-37-2

(R)-Mirtazapine

Purity: ≥98%

Molecular weight: 265.35g/mol

Ref: 54-BUP01567

(R)-Mirtazapine

CAS: 61364-37-2

Formula: C₁₇H₁₉N₃

Color and Shape: White To Off-White Solid

Molecular weight: 265.36

Ref: 4Z-M-1016

(R)-Mirtazapine-13C-d3

CAS: 61364-37-2

Formula: C₁₇H₁₆N₃D₃

Molecular weight: 269.37

Ref: 4Z-M-1018

(R)-Mirtazapine

CAS: 61364-37-2

(R)-Mirtazapine ((R)-Org3770) is a 5-HT3 receptor antagonist, a potential analgesic with anti-injury perception properties.

Formula: C₁₇H₁₉N₃

Purity: 99.75%

Color and Shape: Solid

Molecular weight: 265.35

Ref: TM-T12632

R-Mirtazapine

Controlled Product

CAS: 61364-37-2

Applications R-Mirtazapine is an enantiomer of Mirtazapine (M365000); an antidepressant. R-Mirtazapine showed antinociceptive effects in acute thermal nociception, whereas S-Mirtazapine showed pronociceptive effects.
References Muth-Selbach, Uta., et al.: Brain Res. Bull., 79(1), 63-68 (2009); Smith, Donald F., et al.: Psychopharmacology, 200(2), 273-279 (2008); Freynhagen, Rainer., et al.: Brain Res. Bull., 69(2), 168-173 (2006)

Formula: C₁₇H₁₉N₃

Color and Shape: Neat

Molecular weight: 265.35

Ref: TR-M364995

(R)-Mirtazapine

CAS: 61364-37-2

Formula: C₁₇H₁₉N₃

Molecular weight: 265.36

Ref: ST-EA-CP-M49020