CAS 61379-65-5: Rifamycin, 3-[[(4-cyclopentyl-1-piperazinyl)imino]methyl]-

Description: Rifamycin, 3-[[(4-cyclopentyl-1-piperazinyl)imino]methyl]- is a synthetic derivative of rifamycin, a class of antibiotics known for their efficacy against bacterial infections, particularly those caused by Mycobacterium tuberculosis. This compound features a complex structure that includes a rifamycin core, which is characterized by a naphthalenic ring system and a characteristic ansa bridge. The presence of the 4-cyclopentyl-1-piperazinyl group enhances its pharmacological properties, potentially improving its ability to penetrate bacterial cell walls and interact with RNA polymerase, thereby inhibiting bacterial RNA synthesis. The CAS number 61379-65-5 uniquely identifies this compound in chemical databases, facilitating research and regulatory processes. Rifamycin derivatives are often explored for their therapeutic potential, particularly in treating resistant strains of bacteria, and their structural modifications can influence their antibacterial activity, solubility, and bioavailability. As with many antibiotics, the development and use of this compound must be carefully managed to mitigate the risk of resistance development in bacterial populations.

Formula: C₄₇H₆₄N₄O₁₂

InChI: InChI=1S/C47H64N4O12/c1-24-13-12-14-25(2)46(59)49-37-32(23-48-51-20-18-50(19-21-51)31-15-10-11-16-31)41(56)34-35(42(37)57)40(55)29(6)44-36(34)45(58)47(8,63-44)61-22-17-33(60-9)26(3)43(62-30(7)52)28(5)39(54)27(4)38(24)53/h12-14,17,22-24,26-28,31,33,38-39,43,53-57H,10-11,15-16,18-21H2,1-9H3,(H,49,59)/b13-12+,22-17+,25-14-,48-23?/t24-,26+,27+,28+,33-,38-,39+,43+,47-/m0/s1

InChI key: InChIKey=WDZCUPBHRAEYDL-LYDPARFQSA-N

SMILES: O=C(OC1C(C)C(OC)C=COC2(OC3=C(C2=O)C4=C(O)C(C=NN5CCN(CC5)C6CCCC6)=C(NC(=O)C(=CC=CC(C)C(O)C(C)C(O)C1C)C)C(O)=C4C(O)=C3C)C)C

Synonyms:

• 2,7-(Epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan, rifamycin deriv.
• 3-[[(4-Cyclopentyl-1-piperazinyl)imino]methyl]rifamycin
• Antibiotic DL 473IT
• Cyclopentylrifampicin
• Dl 473
• Ktc 1
• Mdl 473
• Prifitin
• Priftin
• R 77-3
• Rifamycin AF/ACPP
• Rifapentin
• Rifapentina
• Rifapentine

Rifapentine

CAS: 61379-65-5

Rifapentine (Rifapentinum) is a long-acting, cyclopentyl-substituted derivative of rifamycin used to treat mycobacterium infections.

• Formula: C₄₇H₆₄N₄O₁₂
• Purity: 95.74% - ≥98%
• Color and Shape: Solid
• Molecular weight: 877.03

Rifamycin, 3-[[(4-cyclopentyl-1-piperazinyl)imino]methyl]-

CAS: 61379-65-5

• Formula: C₄₇H₆₄N₄O₁₂
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 877.0307

Rifapentine

CAS: 61379-65-5

• Formula: C₄₇H₆₄N₄O₁₂
• Color and Shape: Brownish-Red Solid
• Molecular weight: 877.05

Rifapentine-15N

CAS: 61379-65-5

• Formula: C₄₇H₆₄N₃₁₅NO₁₂
• Color and Shape: Red Solid
• Molecular weight: 878.04

Rifapentine-d9

CAS: 61379-65-5

• Formula: C₄₇H₅₅D₉N₄O₁₂
• Color and Shape: Red Solid
• Molecular weight: 886.10

Rifampicin S-Na Sodium

CAS: 61379-65-5

• Purity: 97%
• Molecular weight: 877.03g/mol

Rifapentine

CAS: 61379-65-5

• Formula: C₄₇H₆₄N₄O₂
• Purity: (HPLC) ≥ 95.0%
• Color and Shape: Red to dark red-brown crystalline powder
• Molecular weight: 717.04

Rifapentine, 95%

CAS: 61379-65-5

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Purity: 95%
• Color and Shape: Red to dark red, Crystalline powder

Rifapentine

CAS: 61379-65-5

• Formula: C₄₇H₆₄N₄O₁₂
• Purity: >98.0%(HPLC)
• Color and Shape: Light yellow to Brown powder to crystal
• Molecular weight: 877.05

Rifapentine-D8

CAS: 61379-65-5

• Formula: C₄₇H₅₆D₈N₄O₁₂
• Color and Shape: Neat
• Molecular weight: 885.08

Rifapentine

CAS: 61379-65-5

Applications Semi-synthetic rifamycin. Antibacterial (tuberculostatic). References Arioli, V., et al.: J. Antibiot., 34, 1026 (1981), …

• Formula: C₄₇H₆₄N₄O₁₂
• Color and Shape: Red
• Molecular weight: 877.03

Rifapentine N-Oxide

CAS: 61379-65-5

Applications Rifampicin N-Oxide is related to Rifapentine(R508500) a compound with antibacterial properties. References Arioli, V., …

• Formula: C₄₇H₆₄N₄O₁₃
• Color and Shape: Dark Red To Dark Brown
• Molecular weight: 893.03

Rifapentine

CAS: 61379-65-5

Please enquire for more information about Rifapentine including the price, delivery time and more detailed …

• Formula: C₄₇H₆₄N₄O₁₂
• Purity: Min. 95 Area-%
• Color and Shape: Orange Red Powder
• Molecular weight: 877.03 g/mol