CAS 6138-56-3

Tripelennamine citrate

Description:

Tripelennamine citrate is an antihistamine compound primarily used for its antiallergic properties. It is a salt formed from tripelennamine, a first-generation antihistamine, and citric acid. This substance is characterized by its ability to block histamine H1 receptors, thereby alleviating symptoms associated with allergic reactions, such as itching, sneezing, and runny nose. Tripelennamine citrate is typically administered orally and is known for its sedative effects, which can be attributed to its ability to cross the blood-brain barrier. The compound is also recognized for its potential side effects, including drowsiness, dry mouth, and dizziness, which are common among first-generation antihistamines. In terms of chemical structure, tripelennamine features a diphenylmethane backbone, contributing to its pharmacological activity. It is important to note that while effective, the use of tripelennamine citrate should be approached with caution, particularly in populations sensitive to sedative effects or those taking other central nervous system depressants.

Formula: C₁₆H₂₁N₃·C₆H₈O₇

InChI: InChI=1S/C16H21N3.C6H8O7/c1-18(2)12-13-19(16-10-6-7-11-17-16)14-15-8-4-3-5-9-15;7-3(8)1-6(13,5(11)12)2-4(9)10/h3-11H,12-14H2,1-2H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

InChI key: InChIKey=GGRBYIUPUOYRLQ-UHFFFAOYSA-N

SMILES: N(CC1=CC=CC=C1)(CCN(C)C)C2=CC=CC=N2.C(CC(O)=O)(CC(O)=O)(C(O)=O)O

Synonyms:

• 1,2-Ethanediamine, N,N-dimethyl-N′-(phenylmethyl)-N′-2-pyridinyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
• Tripelennamine citrate
• 2-[Benzyl[2-(dimethylamino)ethyl]amino]pyridine dihydrogen citrate
• Pyridine, 2-[benzyl[2-(dimethylamino)ethyl]amino]-, citrate (1:1)
• 1,2-Ethanediamine, N1,N1-dimethyl-N2-(phenylmethyl)-N2-2-pyridinyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)

Tripelennamine citrate

CAS: 6138-56-3

Tripelennamine citrate, an ethylenediamine derivative, blocks H1 receptors to treat allergies and anaphylaxis.

Formula: C₂₂H₂₉N₃O₇

Color and Shape: Solid

Molecular weight: 447.488

Ref: TM-T62669