CymitQuimica logo

CAS 61380-40-3

:

Lofentanil

Description:
Lofentanil is a synthetic opioid analgesic that is structurally related to fentanyl, designed for use in pain management, particularly in medical settings. It is characterized by its high potency, which is significantly greater than that of morphine, making it effective in treating severe pain. Lofentanil acts primarily on the mu-opioid receptors in the central nervous system, leading to analgesic effects, sedation, and potential respiratory depression. Due to its potency, it requires careful dosing and monitoring to avoid overdose and adverse effects. The substance is typically administered in controlled environments, such as hospitals, and is not commonly available for general use. Its chemical structure includes a piperidine ring, contributing to its lipophilicity and ability to cross the blood-brain barrier efficiently. As with other opioids, there is a risk of dependence and abuse associated with lofentanil, necessitating stringent regulations regarding its use and distribution.
Formula:C25H32N2O3
InChI:InChI=1/C25H32N2O3/c1-4-23(28)27(22-13-9-6-10-14-22)25(24(29)30-3)16-18-26(19-20(25)2)17-15-21-11-7-5-8-12-21/h5-14,20H,4,15-19H2,1-3H3/t20-,25+/s2
InChI key:InChIKey=IMYHGORQCPYVBZ-QTZDTBTRNA-N
SMILES:N(C(CC)=O)([C@@]1(C(OC)=O)[C@@H](C)CN(CCC2=CC=CC=C2)CC1)C3=CC=CC=C3
Synonyms:
  • Lofentanil
  • 4-Piperidinecarboxylic acid, 3-methyl-4-[(1-oxopropyl)phenylamino]-1-(2-phenylethyl)-, methyl ester, (3R,4S)-rel-(-)-
  • 4-Piperidinecarboxylic acid, 3-methyl-4-[(1-oxopropyl)phenylamino]-1-(2-phenylethyl)-, methyl ester, cis-(-)-
Sort by
The purity filter is not visible because current products do not have associated purity data for filtering.
Found 2 products.
  • Lofentanil
    TRC
    + Info

    Lofentanil

    Controlled Product
    CAS:

    Applications Lofentanil is a very potent and long-acting opiate agonist.
    Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
    References Lembeck, F., Donnerer, J.: Eur. J. Pharmacol., 114, 241 (1985)

    Formula:C25H32N2O3
    Color and Shape:Neat
    Molecular weight:408.53

    Ref: TR-L469375

    1mg
    638.00€
    10mg
    4,105.00€
  • Lofentanil (1.0mg/ml in Acetonitrile)
    TRC
    + Info

    Lofentanil (1.0mg/ml in Acetonitrile)

    Controlled Product
    CAS:
    Formula:C25H32N2O3
    Color and Shape:Single Solution
    Molecular weight:408.53

    Ref: TR-KIT5515

    1x1ml
    1,027.00€