CAS 614-03-9

(+)-Phenylephrine

Description:

(+)-Phenylephrine is a synthetic sympathomimetic amine primarily used as a decongestant and vasopressor. It is characterized by its ability to selectively stimulate alpha-1 adrenergic receptors, leading to vasoconstriction and increased blood pressure. This compound is typically encountered as a white to off-white crystalline powder, and it is soluble in water and alcohol, which facilitates its use in various pharmaceutical formulations. The molecular formula of (+)-Phenylephrine is C9H13NO2, and it has a molecular weight of approximately 167.21 g/mol. Its stereochemistry is significant, as the (+) enantiomer is the active form that exhibits the desired pharmacological effects. In addition to its therapeutic applications, (+)-Phenylephrine is also used in ophthalmology to induce mydriasis (pupil dilation) without affecting accommodation. Safety and efficacy profiles are well-documented, but it is important to monitor for potential side effects, such as hypertension and reflex bradycardia, particularly in sensitive populations. Overall, (+)-Phenylephrine is a valuable compound in both clinical and over-the-counter medications.

Formula: C₉H₁₃NO₂

InChI: InChI=1S/C9H13NO2/c1-10-6-9(12)7-3-2-4-8(11)5-7/h2-5,9-12H,6H2,1H3/t9-/m1/s1

InChI key: InChIKey=SONNWYBIRXJNDC-SECBINFHSA-N

SMILES: [C@H](CNC)(O)C1=CC(O)=CC=C1

Synonyms:

• (+)-Phenylephrine
• (+)-m-Synephrine
• (S)-3-Hydroxy-alpha-((methylamino)methyl)benzyl alcohol
• (S)-3-hydroxy-α-[(methylamino)methyl]benzyl alcohol
• (αS)-3-Hydroxy-α-[(methylamino)methyl]benzenemethanol
• 3-[(1S)-1-hydroxy-2-(methylamino)ethyl]phenol
• <span class="text-smallcaps">L</span>-(+)-Phenylephrine
• Benzenemethanol, 3-hydroxy-α-[(methylamino)methyl]-, (S)-
• Benzenemethanol, 3-hydroxy-α-[(methylamino)methyl]-, (αS)-
• Benzyl alcohol, m-hydroxy-α-[(methylamino)methyl]-, (+)-
• d-Phenylephrine

(S)-Phenylephrine

CAS: 614-03-9

Formula: C₉H₁₃NO₂

Molecular weight: 167.21

Ref: ST-EA-CP-P12015

L-Phenylephrine

CAS: 614-03-9

L-Phenylephrine is an alpha-adrenergic agonist used as a mydriatic, nasal decongestant, and cardiotonic agent.

Formula: C₉H₁₃NO₂

Color and Shape: Solid

Molecular weight: 167.21

Ref: TM-T68997